Evidence map›Paper›PMID 24266717›Full record

ArticleThe British journal of dermatology2014

Patient satisfaction with treatments for moderate-to-severe plaque psoriasis in clinical practice.

K Callis Duffin, H Yeung, J Takeshita, G G Krueger, A D Robertson, A B Troxel, D B Shin, A S Van Voorhees, J M Gelfand

Open access · greenAbstract readComparative Study
In one paragraph

Article in The British journal of dermatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 95 citations in OpenAlex.

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  14. Recommendations for Initiating Systemic Therapy in Patients with Psoriasis.The Journal of clinical and aesthetic dermatology · 2019
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

K Callis Duffin *Department of Dermatology, University of Utah School of Medicine, Salt Lake City, UT, USA.
H Yeung *Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
J TakeshitaDepartment of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
G G KruegerDepartment of Dermatology, University of Utah School of Medicine, Salt Lake City, UT, USA.
A D RobertsonNational Psoriasis Foundation, Portland, OR, USA.
A B TroxelCenter for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
D B ShinDepartment of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
A S Van VoorheesDepartment of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
J M GelfandDepartment of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
University of Pennsylvania · USUniversity of Utah · USASIS Foundation · USYale University · US

Funding

Penn Dermatology Research Training ProgramT32AR007465 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI Elizabeth Anne Grice, David Joel Margolis · 1986 to 2026
$9.0M
Clinical Pharmacoepidemiology Training ProgramT32GM075766 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Sean Hennessy, Charles Edward Leonard · 2006 to 2026
$8.4M
Mentored Scholars Program for Translational Comparative Effectiveness ResearchKM1CA156723 · NCI · UNIVERSITY OF UTAH · PI BYINGTON, CARRIE L. · 2010 to 2010
$2.5M
Comparative Effectiveness of Biologics for PsoriasisRC1AR058204 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI GELFAND, JOEL M · 2009 to 2010
$1.0M
Psoriasis and the Risk of DiabetesK24AR064310 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI GELFAND, JOEL M · 2013 to 2017
$870k
NCI NIH HHS 1KM1CA156723NCI NIH HHS KM1 CA156723NIAMS NIH HHS K24 AR064310NIAMS NIH HHS K24-AR064310NIAMS NIH HHS RC1-AR058204NIAMS NIH HHS T32 AR007465NIAMS NIH HHS T32-AR07465NIGMS NIH HHS T32 GM075766NIGMS NIH HHS T32-GM075766-6
6 · The paper itself

Abstract

backgroundTreatment satisfaction among patients with moderate-to-severe psoriasis has not been studied and compared across treatments using a validated instrument.

objectivesTo assess patient-reported satisfaction with systemic and phototherapy treatments for moderate-to-severe psoriasis in clinical practice and to correlate satisfaction with disease severity and quality-of-life measures.

methodsThis was a cross-sectional study of 1182 patients with moderate-to-severe psoriasis in the Dermatology Clinical Effectiveness Research Network in the U.S.A. Patients receiving either topical therapies only; monotherapy with oral systemic therapies, biologics or narrowband ultraviolet B phototherapy; or combination therapy with biologics and methotrexate completed the Treatment Satisfaction Questionnaire for Medication version II.

resultsMedian unadjusted overall satisfaction scores were highest for patients receiving biologic monotherapies, biologic-methotrexate combinations, or phototherapy (83.3); scores were lowest for those receiving topical therapies only or acitretin (66.7). In fully adjusted models, compared with patients receiving methotrexate monotherapy, those receiving adalimumab, etanercept, ustekinumab, phototherapy or adalimumab with methotrexate had significantly higher median overall satisfaction scores by 7.2-8.3 points, while those receiving topical therapies only had significantly lower overall satisfaction by 8.9 points. Adjusted convenience scores were lowest for patients receiving topical therapies only or infliximab. Modest but significant correlations were found between the overall satisfaction subscale and both the Psoriasis Area and Severity Index (ρ = -0.36, P < 0.001) and the Dermatology Life Quality Index (ρ = -0.47, P < 0.001).

conclusionsDiscernible differences were found in treatment satisfaction among therapies, particularly regarding treatment effectiveness and convenience. Further application of treatment satisfaction measures may inform treatment decisions and guideline development.

Indexed as

Patient SatisfactionAdultCross-Sectional StudiesDermatologic AgentsFemaleHumansMaleMiddle AgedPsoriasisQuality of LifeSurveys and QuestionnairesTreatment OutcomeUltraviolet TherapyDermatologic Agents

Identifiers

PMID24266717
PMCPMC4302409
OpenAlexW2030972148

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.