ArticleJournal of the Korean Surgical Society2013
Antiadhesive effect and safety of sodium hyaluronate-carboxymethyl cellulose membrane in thyroid surgery.
Article in Journal of the Korean Surgical Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Effect of an anti-adhesion agent on vision-based assessment of cervical adhesions after thyroid surgery: randomized, placebo-controlled trial.Scientific reports · 2021Trial
- Outcomes and retear rates after subacromial and glenohumeral injection of a chitosan-based thermosensitive anti-adhesive agent during arthroscopic rotator cuff repair: a propensity score-matched analysis.Clinics in shoulder and elbow · 2026Article
- Comparison of four commercially available adhesion barriers after open thyroid surgery: a prospective observational study.Annals of surgical treatment and research · 2026Article
- The safety and anti-adhesive effect of acellular dermal matrix application after thyroid surgery: a multicenter randomized controlled trial.Annals of surgical treatment and research · 2025Article
- Anti-adhesive effect and safety of a thermosensitive adhesion barrier (Mediclore) for thyroid surgery: a double-blinded randomized controlled trial.Annals of surgical treatment and research · 2022Article
- Effect of Extractum cepae, heparin sodium and allantoin combination (ContractubexNorthern clinics of Istanbul · 2022Article
- Ultrasound-Guided Thermal Ablation of Thyroid Nodules: Technicalities Progress and Clinical Applications, Especially in Malignant Thyroid Nodules.Frontiers in oncology · 2021Review
- Thyroid cancer surgery - in what direction are we going? A mini-review.The Journal of international medical research · 2020Review
- Robotic thyroidectomy and cervical neck dissection for thyroid cancer.Gland surgery · 2016Review
- Reduced incidence of postoperative symptoms following a novel bilateral supraclavicular approach to open thyroidectomy: a randomized clinical trial in a Chinese population.International journal of clinical and experimental medicine · 2015Article
- Evaluation of the effects of hyaluronic acid-carboxymethyl cellulose barrier on ovarian tumor progression.Journal of ovarian research · 2014Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeA number of researchers have suggested the use of sodium hyaluronate carboxymethyl cellulose (HA-CMC) membrane for preventing postoperative adhesion. This study evaluated the antiadhesive effect and safety of HA-CMC membrane in thyroidectomy for papillary thyroid cancer.
methodsOne hundred sixty-two patients who underwent thyroidectomy were prospectively randomized. In the study group of 80 patients, the 7.5 cm × 13 cm HA-CMC membrane was applied to the operative field after thyroidectomy. The subjects were asked about complications including adhesive symptoms using an 8-item questionnaire at 2 weeks, 3 months, and 6 months after surgery. In addition, items on the appearance of neck wrinkles and scars were evaluated by a physician who had no information about the patient's allocation.
resultsThere were no significant differences in complications such as swallowing difficulty, and wrinkles between study and control groups. Both groups presented significantly decreased scores over time in swallowing difficulty, and wrinkles. There were no complications regarding the HA-CMC membrane.
conclusionThe antiadhesive effect of HA-CMC membrane in thyroid surgery is still uncertain, although it is biologically safe. Further investigation is needed to confirm the antiadhesive effect of HA-CMC membrane in thyroid surgery.
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