ArticleInterventional medicine & applied science2013
Effects of low-intensity concentric and eccentric exercise combined with blood flow restriction on indices of exercise-induced muscle damage.
Article in Interventional medicine & applied science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05617911 (Clinical Comparison of Patellofemoral Pain Syndrome Outcomes After Blood Flow Restriction Therapy), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Comparison of Patellofemoral Pain Syndrome Outcomes After Blood Flow Restriction Therapy
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Low-Load Blood-Flow Restriction Exercise to Failure and Nonfailure and Myoelectric Activity: A Meta-Analysis.Journal of athletic training · 2022Pooled it
- Effect of resistance training with blood flow restriction on muscle damage markers in adults: A systematic review.PloS one · 2021Pooled it
- Acute Responses to High-Intensity Back Squats with Bilateral Blood Flow Restriction.International journal of environmental research and public health · 2023Trial
- Trial
- Patterns of responses and time-course of changes in muscle size and strength during low-load blood flow restriction resistance training in women.European journal of applied physiology · 2021Trial
- Eccentric and concentric blood flow restriction resistance training on indices of delayed onset muscle soreness in untrained women.European journal of applied physiology · 2019Trial
- Effects of blood flow restriction during moderate-intensity eccentric knee extensions.The journal of physiological sciences : JPS · 2018Trial
- The effect of eccentric exercise with blood flow restriction on neuromuscular activation, microvascular oxygenation, and the repeated bout effect.European journal of applied physiology · 2017Trial
- Impact of exercise with blood flow restriction on muscle hypertrophy and performance outcomes in men and women.PloS one · 2025Article
- Effects of a Perioperative Blood Flow Restriction Therapy Program on Early Quadriceps Strength and Patient-Reported Outcomes After Anterior Cruciate Ligament Reconstruction.Orthopaedic journal of sports medicine · 2023Article
- An Automated Technique for the Measurement of Limb Occlusion Pressure During Blood Flow Restriction Therapy Is Equivalent to Previous Gold Standard.Arthroscopy, sports medicine, and rehabilitation · 2022Article
- Review
- Effects of functional electro-stimulation combined with blood flow restriction in affected muscles by spinal cord injury.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Variations in Muscle Activity and Exerted Torque During Temporary Blood Flow Restriction in Healthy Individuals.Frontiers in bioengineering and biotechnology · 2021Article
- The Evolution of Blood Flow Restricted Exercise.Frontiers in physiology · 2021Review
- Article
- A Portable Passive Rehabilitation Robot for Upper-Extremity Functional Resistance Training.IEEE transactions on bio-medical engineering · 2019Article
- Tensiomyography parameters and serum biomarkers after eccentric exercise of the elbow flexors.European journal of applied physiology · 2019Article
- Blood Flow Restriction Exercise: Considerations of Methodology, Application, and Safety.Frontiers in physiology · 2019Review
- Application of Blood Flow Restriction to Optimize Exercise Countermeasures for Human Space Flight.Frontiers in physiology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledLow-intensity blood-flow restriction (BFR) resistance training significantly increases strength and muscle size, but some studies report it produces exercise-induced muscle damage (EIMD) in the lower body after exercise to failure. PURPOSE: To investigate the effects of a pre-set number of repetitions of upper body concentric and eccentric exercise when combined with BFR on changes in EIMD.
methodsTen young men had arms randomly assigned to either concentric BFR (CON-BFR) or eccentric BFR (ECC-BFR) dumbbell curl exercise (30% one-repetition maximum (1-RM), 1 set of 30 repetitions followed by 3 sets of 15 repetitions). Maximal isometric voluntary contraction force (MVC), muscle thickness (MTH), circumference, range of motion (ROM), ratings of perceived exertion (RPE), and muscle soreness were measured before, immediately after, and daily for 4 days post-exercise.
resultsMVC decreased by 36% for CON-BFR and 12% for ECC-BFR immediately after exercise but was not changed 1-4 days post-exercise (p > 0.05). Only CON-BFR had significant changes in MTH and circumference immediately after exercise (p < 0.05). Muscle soreness was observed in the ECC-BFR arm at 1 and 2 days after exercise.
conclusionsLow-intensity ECC-BFR produces significant muscle soreness at 24 h but neither ECC-BFR nor CON-BFR exercise produces significant changes in multiple indices of EIMD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.