ArticlePloS one2013
Differences in survival between colon and rectal cancer from SEER data.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
95 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Survival Rate of Colorectal Cancer in Iran: A Systematic Review and Meta-AnalysisAsian Pacific journal of cancer prevention : APJCP · 2019Pooled it
- Bevacizumab Combined with Chemotherapy Improves Survival for Patients with Metastatic Colorectal Cancer: Evidence from Meta Analysis.PloS one · 2016Pooled it
- Final Results of ERBIMOX: A Randomized Phase II Study of Modified FOLFOX7 With or Without Cetuximab as First-Line Treatment for KRAS Wild-type Metastatic Colorectal Cancer.Journal of gastrointestinal cancer · 2025Trial
- Chinese herbal medicine (JianPi-BuShen) and completion rate of adjuvant chemotherapy for patients with stage II and III colon cancer: A randomized clinical trial.European journal of cancer (Oxford, England : 1990) · 2024Trial
- Development and validation of prediction models for the prognosis of colon cancer with lung metastases: a population-based cohort study.Frontiers in endocrinology · 2023Trial
- Tumour location and efficacy of first-line EGFR inhibitors inESMO open · 2019Trial
- Long-term survival and clinical characteristics of colon and rectal cancer: a comprehensive 47-year retrospective analysis using the SEER database.Annals of medicine and surgery (2012) · 2026Article
- Ten-Year Outcomes in Colorectal Cancer-Competing Risks and Patient Vulnerability: A Prospective Multicenter Observational Study.Journal of clinical medicine · 2026Article
- The tumor-suppressive function of the unique H domain of FCGBP and its potential as a therapeutic target in colorectal cancer.BMC cancer · 2026Article
- Prospective validation of the modified metastatic colorectal cancer score (mCCS) in >600 patients with RAS-wild-type metastatic colorectal cancer treated with first-line panitumumab plus FOLFIRI/FOLFOX: Final results of the non-interventional study VALIDATE.International journal of cancer · 2026Article
- Whole genome sequencing data of early- and late-onset colorectal cancer in 99 Korean patients.Scientific data · 2026Article
- MAP-SCTNet: multi-scale pyramid and frequency-enhanced network for colorectal cancer histopathological image segmentation.Frontiers in medicine · 2026Article
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- Watch and wait in locally advanced rectal cancer: Evolution, current evidence, and future directions.World journal of gastrointestinal surgery · 2025Review
- Distinctive chromosomal, mutational and transcriptional profiling in colon versus rectal cancers.Journal of translational medicine · 2025Article
- Article
- Impact of emergency presentation on early surgical and oncological outcomes in rectosigmoid cancer: a single-center retrospective analysis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
- Article
- OncoE25: an AI model for predicting postoperative prognosis in early-onset stage I-III colon and rectal cancer-a population-based study using SEER with dual-center cohort validation.Journal of translational medicine · 2025Article
- Article
35 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLittle is known about colorectal cancer or colon and rectal cancer. Are they the same disease or different diseases?
objectivesThe aim of this epidemiology study was to compare the features of colon and rectal cancer by using recent national cancer surveillance data. DESIGN AND
settingData included colorectal cancer (1995-2008) from the Surveillance, Epidemiology, and End Results Program (SEER) database. Only adenocarcinoma was included for analysis. PATIENTS: A total of 372,130 patients with a median follow-up of 32 months were analyzed.
main outcome measuresMean survival of patients with the same stage of colon and rectal cancer was evaluated.
resultsAround 35% of patients had stage information. Among them, colon cancer patients had better survival than those with rectal cancer, by a margin of 4 months in stage IIB. In stage IIIC and stage IV, rectal cancer patients had better survival than colon cancer patients, by about 3 months. Stage IIB colorectal cancer patients had a poorer prognosis than those with stage IIIA and IIIB colorectal cancer. After adjustment of age, sex and race, colon cancer patients had better survival than rectal cancer of stage IIB, but in stage IIIC and IV, rectal cancer patients had better survival than colon cancer. LIMITATIONS: The study is limited by its retrospective nature.
conclusionThis was a population-based study. The prognosis of rectal cancer was not worse than that of colon cancer. Local advanced colorectal cancer had a poorer prognosis than local regional lymph node metastasis. Stage IIB might require more aggressive chemotherapy, and no less than that for stage III.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.