Evidence map›Paper›PMID 24265564›Full record

ArticleKorean journal of radiology

MR imaging in patients with suspected liver metastases: value of liver-specific contrast agent gadoxetic acid.

Kyung Hee Lee, Jeong Min Lee, Ji Hoon Park, Jung Hoon Kim, Hee Sun Park, Mi Hye Yu, Jeong-Hee Yoon, Joon Koo Han, Byung Ihn Choi

Abstract read
In one paragraph

Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Diagnostic performance of [European radiology · 2019
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  15. [Application of MRI-based Radiomics Models in the Assessment of Hepatic Metastasis of Rectal Cancer].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kyung Hee LeeDivision of Abdominal Imaging, Department of Radiology, Seoul National University College of Medicine, Seoul 110-744, Korea.
Jeong Min Lee
Ji Hoon Park
Jung Hoon Kim
Hee Sun Park
Mi Hye Yu
Jeong-Hee Yoon
Joon Koo Han
Byung Ihn Choi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the diagnostic performance of gadoxetic acid-enhanced magnetic resonance (MR) imaging with that of triple-phase multidetector-row computed tomography (MDCT) in the detection of liver metastasis. MATERIALS AND

methodsOur institutional review board approved this retrospective study and waived informed consent. The study population consisted of 51 patients with hepatic metastases and 62 patients with benign hepatic lesions, who underwent triple-phase MDCT and gadoxetic acid-enhanced MRI within one month. Two radiologists independently and randomly reviewed MDCT and MRI images regarding the presence and probability of liver metastasis. In order to determine additional value of hepatobiliary-phase (HBP), the dynamic-MRI set alone and combined dynamic-and-HBP set were evaluated, respectively. The standard of reference was a combination of pathology diagnosis and follow-up imaging. For each reader, diagnostic accuracy was compared using the jackknife alternative free-response receiver-operating-characteristic (JAFROC).

resultsFor both readers, average JAFROC figure-of-merit (FOM) was significantly higher on the MR image sets than on the MDCT images: average FOM was 0.582 on the MDCT, 0.788 on the dynamic-MRI set and 0.847 on the combined HBP set, respectively (p < 0.0001). The differences were more prominent for small (≤ 1 cm) lesions: average FOM values were 0.433 on MDCT, 0.711 on the dynamic-MRI set and 0.828 on the combined HBP set, respectively (p < 0.0001). Sensitivity increased significantly with the addition of HBP in gadoxetic acid-enhanced MR imaging (p < 0.0001).

conclusionGadoxetic acid-enhanced MRI shows a better performance than triple-phase MDCT for the detection of hepatic metastasis, especially for small (≤ 1 cm) lesions.

Indexed as

Gadolinium DTPAAdultAgedAged, 80 and overContrast MediaDiagnosis, DifferentialFemaleHumansLiver NeoplasmsMagnetic Resonance ImagingMaleMiddle AgedMultidetector Computed TomographyRetrospective StudiesROC CurveContrast MediaGadolinium DTPAgadolinium ethoxybenzyl DTPAComputed tomographyGadoxetic acidHepatic metastasisMagnetic resonance imaging

Identifiers

PMID24265564
PMCPMC3835636

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.