Evidence map›Paper›PMID 24265538›Full record

ArticleJournal of Korean medical science2013

ANCA-negative Wegener's granulomatosis with multiple lower cranial nerve palsies.

Sung-Hee Kim, Jin Park, Jung Ho Bae, Min-Sun Cho, Kee Duk Park, Jee Hyang Jeong

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of Korean medical science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sung-Hee KimDepartment of Neurology, Ewha Womans University School of Medicine and Ewha Medical Research Institute, Seoul, Korea.
Jin Park
Jung Ho Bae
Min-Sun Cho
Kee Duk Park
Jee Hyang Jeong
Ewha Womans University Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wegener's granulomatosis (WG) is a systemic vasculitis affecting small and medium-sized vessels with granulomatous formation. Though it is known for respiratory tract and kidney involvement, neurologic manifestation has been also reported. Herein we report a patient who suffered pansinusitis with multiple lower cranial nerve palsies but reached remission by immunosuppressant after the diagnosis of WG. A 54-yr-old female visited with headache, hearing difficulty, and progressive bulbar symptoms. She experienced endoscopic sinus surgeries due to refractory sinusitis. Neurologic examination revealed multiple lower cranial nerve palsies. Vasculitic markers showed no abnormality. Nasal biopsy revealed granulomatous inflammation and vasculitis involving small vessels. Given cyclophosphamide and prednisolone, her symptoms were prominently improved. WG should be considered in the patient with multiple cranial nerve palsies, especially those with paranasal sinus disease. Because WG can be lethal if delayed in treatment, prompt immunosuppressant is warranted after the diagnostic tissue biopsy.

Indexed as

Antibodies, Antineutrophil CytoplasmicAnti-Inflammatory AgentsAntineoplastic Agents, AlkylatingCranial Nerve DiseasesCyclophosphamideDiagnosis, DifferentialFemaleGranulomatosis with PolyangiitisHumansMiddle AgedPrednisoloneRadionuclide ImagingSinusitisVasculitisAntibodies, Antineutrophil CytoplasmicAnti-Inflammatory AgentsAntineoplastic Agents, AlkylatingCyclophosphamidePrednisolonec-ANCA NegativeCranial Nerve DiseasesRefractory SinusitisWegener Granulomatosis

Identifiers

PMID24265538
PMCPMC3835517
OpenAlexW2169247814

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.