Evidence map›Paper›PMID 24265235›Full record

ReviewComprehensive Physiology2013

Particle transport and deposition: basic physics of particle kinetics.

Akira Tsuda, Frank S Henry, James P Butler

Abstract readReview
In one paragraph

Review in Comprehensive Physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Endothelial Cell Regulation of Lipid Uptake During Feeding and Fasting.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Use of quantitativeFrontiers in toxicology · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Review

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Akira TsudaHarvard School of Public Health, Boston, Massachusetts.
Frank S Henry
James P Butler

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
Adult Tissue Morphogenesis: Functional Regulation of Intussusceptive AngiogenesisR01HL094567 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MENTZER, STEVEN · 2009 to 2016
$3.2M
Particles in Developing Lung: Bioengineering ApproachR01HL070542 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI TSUDA, AKIRA · 2003 to 2007
$3.0M
CHAOTIC MIXING OF AEROSOL IN RHYTHMICALLY EXPANDING LUNGR01HL054885 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI TSUDA, AKIRA · 1995 to 2008
$2.3M
Particle kinetics in the postnatally developing lungR01HL074022 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI TSUDA, AKIRA · 2003 to 2007
$1.2M
NHLBI NIH HHS HL054885NHLBI NIH HHS HL070542NHLBI NIH HHS HL074022NHLBI NIH HHS HL094567NHLBI NIH HHS R01 HL054885NHLBI NIH HHS R01 HL070542NHLBI NIH HHS R01 HL074022NHLBI NIH HHS R01 HL094567NIEHS NIH HHS P30 ES000002
6 · The paper itself

Abstract

The human body interacts with the environment in many different ways. The lungs interact with the external environment through breathing. The enormously large surface area of the lung with its extremely thin air-blood barrier is exposed to particles suspended in the inhaled air. The particle-lung interaction may cause deleterious effects on health if the inhaled pollutant aerosols are toxic. Conversely, this interaction can be beneficial for disease treatment if the inhaled particles are therapeutic aerosolized drugs. In either case, an accurate estimation of dose and sites of deposition in the respiratory tract is fundamental to understanding subsequent biological response, and the basic physics of particle motion and engineering knowledge needed to understand these subjects is the topic of this article. A large portion of this article deals with three fundamental areas necessary to the understanding of particle transport and deposition in the respiratory tract. These are: (i) the physical characteristics of particles, (ii) particle behavior in gas flow, and (iii) gas-flow patterns in the respiratory tract. Other areas, such as particle transport in the developing lung and in the diseased lung are also considered. The article concludes with a summary and a brief discussion of areas of future research.

Indexed as

Models, BiologicalAnimalsBiological TransportDiffusionHumansParticulate MatterRespiratory SystemParticulate Matter

Identifiers

PMID24265235
PMCPMC4398662

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.