Evidence map›Paper›PMID 24265222›Full record

ArticleNucleic acids research2014

Saccharomyces genome database provides new regulation data.

Maria C Costanzo, Stacia R Engel, Edith D Wong, Paul Lloyd, Kalpana Karra, Esther T Chan, Shuai Weng, Kelley M Paskov, Greg R Roe, Gail Binkley and 2 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Ecm19 coordinates mitochondrial fission and cellular redox homeostasis.Redox report : communications in free radical research · 2025
    Article
  3. Article
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  7. Article
  8. Article
  9. RegulatorDB: a resource for the analysis of yeast transcriptional regulation.Database : the journal of biological databases and curation · 2017
    Article
  10. Outreach and online training services at the Saccharomyces Genome Database.Database : the journal of biological databases and curation · 2017
    Article
  11. Article
  12. Article
  13. Article
  14. Article
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  18. Article
  19. CoopTFD: a repository for predicted yeast cooperative transcription factor pairs.Database : the journal of biological databases and curation · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Maria C CostanzoDepartment of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.
Stacia R Engel
Edith D Wong
Paul Lloyd
Kalpana Karra
Esther T Chan
Shuai Weng
Kelley M Paskov
Greg R Roe
Gail Binkley
Benjamin C Hitz
J Michael Cherry

Funding

Genomic Resource for the Yeast SaccharomycesU41HG001315 · NHGRI · STANFORD UNIVERSITY · PI CHERRY, J. MICHAEL · 2011 to 2020
$26.4M
NHGRI NIH HHS U41 HG001315
6 · The paper itself

Abstract

The Saccharomyces Genome Database (SGD; http://www.yeastgenome.org) is the community resource for genomic, gene and protein information about the budding yeast Saccharomyces cerevisiae, containing a variety of functional information about each yeast gene and gene product. We have recently added regulatory information to SGD and present it on a new tabbed section of the Locus Summary entitled 'Regulation'. We are compiling transcriptional regulator-target gene relationships, which are curated from the literature at SGD or imported, with permission, from the YEASTRACT database. For nearly every S. cerevisiae gene, the Regulation page displays a table of annotations showing the regulators of that gene, and a graphical visualization of its regulatory network. For genes whose products act as transcription factors, the Regulation page also shows a table of their target genes, accompanied by a Gene Ontology enrichment analysis of the biological processes in which those genes participate. We additionally synthesize information from the literature for each transcription factor in a free-text Regulation Summary, and provide other information relevant to its regulatory function, such as DNA binding site motifs and protein domains. All of the regulation data are available for querying, analysis and download via YeastMine, the InterMine-based data warehouse system in use at SGD.

Indexed as

Databases, GeneticGene Expression Regulation, FungalGenome, FungalBinding SitesGene Regulatory NetworksInternetProtein Structure, TertiarySaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsTranscription, GeneticSaccharomyces cerevisiae ProteinsTranscription Factors

Identifiers

PMID24265222
PMCPMC3965049

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.