ArticleEuropean journal of nuclear medicine and molecular imaging2014
18F-FDG PET/CT impact on testicular tumours clinical management.
Article in European journal of nuclear medicine and molecular imaging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Diagnostic performance of fluorine-18-fluorodeoxyglucose positron emission tomography in the postchemotherapy management of patients with seminoma: systematic review and meta-analysis.BioMed research international · 2014Pooled it
- FDG PET Hybrid Imaging.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026Review
- Nuclear medicine imaging in non-seminomatous germ cell tumors: lessons learned from the past failures.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Review
- How [18F]-FDG-PET/CT Affects Clinical Management of Patients with Germ Cell Tumors in the Real World.Cancers · 2023Article
- Two decades of FDG-PET/CT in seminoma: exploring its role in diagnosis, surveillance and follow-up.Cancer imaging : the official publication of the International Cancer Imaging Society · 2022Article
- Contemporary options and future perspectives: three examples highlighting the challenges in testicular cancer imaging.World journal of urology · 2022Review
- Biparametric magnetic resonance imaging in the surveillance of testicular tumors following radical orchiectomy.Turkish journal of urology · 2020Review
- Molecular Imaging for Evaluation of Viable Testicular Cancer Nodal Metastases.Current urology reports · 2018Review
- The use of F-FDG PET/CT in testicular cancer.Translational andrology and urology · 2018Review
- Update on advances in molecular PET in urological oncology.Japanese journal of radiology · 2016Review
- Controversies in the management of clinical stage I testicular seminoma.Central European journal of urology · 2016Article
- PET/Computed Tomography in Renal, Bladder, and Testicular Cancer.PET clinics · 2015Review
- Diagnostic accuracy of integrated (18)F-FDG PET/CT for restaging patients with malignant germ cell tumours.The British journal of radiology · 2014Article
- Article
Corrections and comments
- Commented on by
- Erratum issuedDomenico, Rubello [corrected to Rubello, Domenico]
Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTesticular tumour is the most common malignancy in young men. The diagnostic work-up is mainly based on morphological imaging. The aim of our study was to evaluate the clinical impact of (18)F-FDG PET/CT in patients with testicular tumour.
methodsWe retrospectively evaluated all patients studied by (18)F-FDG PET/CT at our centre. Inclusion criteria were: pathological confirmation of testicular tumour, contrast-enhanced CT scan performed within a month of the PET/CT scan, and clinical/imaging follow-up performed at the Oncology Unit of our hospital. Overall, 56 patients were enrolled and 121 PET/CT scans were evaluated. (18)F-FDG PET/CT was performed following standard procedures and the results were compared with clinical, imaging and follow-up data. Clinicians were contacted to inquire whether the PET/CT scan influenced the patient's management. Answers were scored as follows: start/continue chemotherapy or radiotherapy, indication for surgery of secondary lesions, and clinical surveillance.
resultsOn a scan basis, 51 seminoma and 70 nonseminoma (NS) cases were reviewed. Of the 121 cases. 32 were found to be true-positive, 74 true-negative, 8 false-positive and 6 false-negative by PET/CT. PET/CT showed good sensitivity and specificity for seminoma lesion detection (92% and 84%, respectively), but its sensitivity was lower for NS forms (sensitivity and specificity 77% and 95%, respectively). The PET/CT scan influenced the clinical management of 47 of 51 seminomas (in 6 chemotherapy was started/continued, in 3 radiotherapy was started/continued, in 2 surgery of secondary lesions was performed, and in 36 clinical surveillance was considered appropriate), and 59 of 70 NS (in 18 therapy/surgery was started/continued, and in 41 clinical surveillance was considered appropriate).
conclusionOur preliminary data demonstrate the potential usefulness of PET/CT for the assessment of patients with testicular tumour. It provides valuable information for the clinical management, particularly for clinical surveillance, post-therapy assessment and when relapse is suspected.
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