Evidence map›Paper›PMID 24262893›Full record

ArticleJournal of biomedical informatics2014

The National Institutes of Health's Biomedical Translational Research Information System (BTRIS): design, contents, functionality and experience to date.

James J Cimino, Elaine J Ayres, Lyubov Remennik, Sachi Rath, Robert Freedman, Andrea Beri, Yang Chen, Vojtech Huser

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Tumour spectrum inJournal of medical genetics · 2025
    Pooled it
  2. Article
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  4. Acute Transient Aminotransferase Elevation is Common With Intrathecal Methotrexate, but Liver Injury is Infrequent.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  5. Article
  6. Article
  7. Clinical Data Warehousing: A Scoping Review.Journal of the Society for Clinical Data Management · 2024
    Article
  8. Artificial Intelligence-Based Medical Data Mining.Journal of personalized medicine · 2022
    Review
  9. Article
  10. The National COVID Cohort Collaborative (N3C): Rationale, design, infrastructure, and deployment.Journal of the American Medical Informatics Association : JAMIA · 2021
    Article
  11. Article
  12. Article
  13. Review
  14. Characterizing Basic and Complex Usage of i2b2 at an Academic Medical Center.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2020
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

James J CiminoLaboratory for Informatics Development, NIH Clinical Center, Bethesda, MD, United States. Electronic address: ciminoj@mail.nih.gov.
Elaine J AyresLaboratory for Informatics Development, NIH Clinical Center, Bethesda, MD, United States.
Lyubov RemennikLaboratory for Informatics Development, NIH Clinical Center, Bethesda, MD, United States.
Sachi RathComputer Sciences Corporation, Falls Church, VA, United States.
Robert FreedmanComputer Sciences Corporation, Falls Church, VA, United States.
Andrea BeriComputer Sciences Corporation, Falls Church, VA, United States.
Yang ChenComputer Sciences Corporation, Falls Church, VA, United States.
Vojtech HuserLaboratory for Informatics Development, NIH Clinical Center, Bethesda, MD, United States.

Funding

Biomedical Translational Research Information System (BTRIS) Data Reuse ProtocolZIACL000904 · CLC · CLINICAL CENTER · PI CIMINO, JAMES · 2009 to 2014
$0k
Improving the Clinical Research Informatics and Clinical Bioinformatics Infrastructure at the NIH Clinical CenterZIACL000907 · CLC · CLINICAL CENTER · PI HUSER, VOJTECH · 2014 to 2014
$0k
Intramural NIH HHS Z01 CL000904Intramural NIH HHS ZIA CL000904
6 · The paper itself

Abstract

The US National Institutes of Health (NIH) has developed the Biomedical Translational Research Information System (BTRIS) to support researchers' access to translational and clinical data. BTRIS includes a data repository, a set of programs for loading data from NIH electronic health records and research data management systems, an ontology for coding the disparate data with a single terminology, and a set of user interface tools that provide access to identified data from individual research studies and data across all studies from which individually identifiable data have been removed. This paper reports on unique design elements of the system, progress to date and user experience after five years of development and operation.

Indexed as

Biological OntologiesDatabase Management SystemsBiomedical ResearchElectronic Health RecordsHumansNational Institutes of Health (U.S.)Translational Research, BiomedicalUnited StatesClinical researchOntologyResearch data repositoryResearch data warehouseTranslational research

Identifiers

PMID24262893
PMCPMC4026354

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.