Evidence map›Paper›PMID 24262650›Full record

ArticleDrug and alcohol dependence2014

Exposure to the Lebanon War of 2006 and effects on alcohol use disorders: the moderating role of childhood maltreatment.

Katherine M Keyes, Dvora Shmulewitz, Eliana Greenstein, Kate McLaughlin, Melanie Wall, Efrat Aharonovich, Abraham Weizman, Amos Frisch, Baruch Spivak, Bridget F Grant and 1 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

  • Erratum issued
    McLaughlin, Kate [corrected to McLaughlin, Katie A]
5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Katherine M KeyesDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA. Electronic address: kmk2104@columbia.edu.
Dvora ShmulewitzNew York State Psychiatric Institute, New York, NY 10032, USA; Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
Eliana GreensteinNew York State Psychiatric Institute, New York, NY 10032, USA; Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
Kate McLaughlinDivision of General Pediatrics, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115-6092, USA.
Melanie WallDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.
Efrat AharonovichNew York State Psychiatric Institute, New York, NY 10032, USA; Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
Abraham WeizmanFelsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Israel.
Amos FrischFelsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Israel.
Baruch SpivakFelsenstein Medical Research Center, Sackler Faculty of Medicine, Tel Aviv University, Israel.
Bridget F GrantLaboratory of Epidemiology and Biometry, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA.
Deborah HasinDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA; New York State Psychiatric Institute, New York, NY 10032, USA; Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
Columbia University · USTel Aviv University · ILBoston Children's Hospital · USNational Institutes of Health · USNew York State Psychiatric Institute

Funding

National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) - IIIZIAAA000449 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI GRANT, BRIDGET F · 2009 to 2016
$16.5M
Alcohol in Israel: Genetic and Environmental EffectsR01AA013654 · NIAAA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI HASIN, DEBORAH S. · 2003 to 2007
$4.6M
Adverse childhood experiences, personality psychopathology, and alcohol disordersU01AA018111 · NIAAA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI HASIN, DEBORAH S · 2009 to 2013
$3.4M
HealthCall: Brief Intervention to Reduce Drug Use in HIV Primary CareR01DA024606 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI AHARONOVICH, EFRAT · 2010 to 2014
$2.9M
Epidemiologic Studies of Alcohol Use Disorders (ongoing)K05AA014223 · NIAAA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HASIN, DEBORAH S · 2003 to 2012
$1.5M
Race, alcohol consumption and vehicle crashes: an epidemiologic paradoxK01AA021511 · NIAAA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KEYES, KATHERINE M. · 2013 to 2017
$904k
Child adversity and the developmental epidemiology of mood and anxiety disorders.K01MH092526 · NIMH · UNIVERSITY OF WASHINGTON · PI MCLAUGHLIN, KATIE · 2011 to 2015
$846k
NIAAA NIH HHS K01 AA021511NIAAA NIH HHS K05 AA014223NIAAA NIH HHS K05AA014223NIAAA NIH HHS R01 AA013654NIAAA NIH HHS R01AA013654,NIAAA NIH HHS U01 AA018111NIAAA NIH HHS U01AA018111NIDA NIH HHS R01 DA024606NIMH NIH HHS K01 MH092526
6 · The paper itself

Abstract

backgroundCivilian populations now comprise the majority of casualties in modern warfare, but effects of war exposure on alcohol disorders in the general population are largely unexplored. Accumulating literature indicates that adverse experiences early in life sensitize individuals to increased alcohol problems after adult stressful experiences. However, child and adult stressful experiences can be correlated, limiting interpretation. We examine risk for alcohol disorders among Israelis after the 2006 Lebanon War, a fateful event outside the control of civilian individuals and uncorrelated with childhood experiences. Further, we test whether those with a history of maltreatment are at greater risk for an alcohol use disorder after war exposure compared to those without such a history.

methodsAdult household residents selected from the Israeli population register were assessed with a psychiatric structured interview; the analyzed sample included 1306 respondents. War measures included self-reported days in an exposed region.

resultsAmong those with a history of maltreatment, those in a war-exposed region for 30+ days had 5.3 times the odds of subsequent alcohol disorders compared to those exposed 0 days (95%C.I. 1.01-27.76), controlled for relevant confounders; the odds ratio for those without this history was 0.5 (95%C.I. 0.25-1.01); test for interaction: X(2)=5.28, df=1, P=0.02.

conclusionsExperiencing a fateful stressor outside the control of study participants, civilian exposure to the 2006 Lebanon War, is associated with a heightened the risk of alcohol disorders among those with early adverse childhood experiences. Results suggest that early life experiences may sensitize individuals to adverse health responses later in life.

Indexed as

Population SurveillanceWarfareAdultAlcohol-Related DisordersChild AbuseChild, PreschoolFemaleHumansLebanonMaleMiddle AgedStress, PsychologicalYoung AdultAlcohol disordersChildhood maltreatmentInteractionIsraelStressWar

Identifiers

PMID24262650
PMCPMC3884580
OpenAlexW2013562861

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.