Evidence map›Paper›PMID 24262627›Full record

ArticleThe Journal of general virology2014

Characterization of a novel Negevirus and a novel Bunyavirus isolated from Culex (Culex) declarator mosquitoes in Trinidad.

Albert J Auguste, Christine V F Carrington, Naomi L Forrester, Vsevolod L Popov, Hilda Guzman, Steven G Widen, Thomas G Wood, Scott C Weaver, Robert B Tesh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of general virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 74 citations in OpenAlex.

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  14. Vertical transmission inProceedings of the National Academy of Sciences of the United States of America · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Albert J AugusteInstitute for Human Infections and Immunity and Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Christine V F CarringtonDepartment of Preclinical Sciences, Faculty of Medical Sciences, University of the West Indies, St. Augustine, Republic of Trinidad and Tobago.
Naomi L ForresterInstitute for Human Infections and Immunity and Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Vsevolod L PopovInstitute for Human Infections and Immunity and Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Hilda GuzmanInstitute for Human Infections and Immunity and Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Steven G WidenDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Thomas G WoodDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Scott C WeaverInstitute for Human Infections and Immunity and Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Robert B TeshInstitute for Human Infections and Immunity and Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
The University of Texas Medical Branch at Galveston · USUniversity of the West Indies · TT

Funding

NIAID NIH HHS HHSN272201000040CNIAID NIH HHS HHSN272201000040IPHS HHS HHSN27200004
6 · The paper itself

Abstract

Pools of mosquitoes were tested for insect-specific viruses using cytopathic effect (CPE) assays on Aedes albopictus (C6/36) cells. Illumina sequencing of RNA from pool TR7094, which produced extensive CPE 2 days post-infection, yielded the complete genome sequences of a previously unknown Bunyavirus, designated Cumuto virus (CUMV), and a second virus designated Wallerfield virus (WALV). WALV shared highest amino acid identity (60.1 %) with Dezidougou virus from Côte d'Ivoire, a positive-sense, single-strand RNA, insect-specific virus belonging to the newly proposed genus Negevirus associated with mosquitoes and phlebotomine sandflies. The S, M and L segments of CUMV were most closely related to those of Gouleako virus, also from Côte d'Ivoire (amino acid identities of 36 %, 38% and 54 % respectively). Neither virus produced CPE on vertebrate cells, or illness in newborn mice. Isolation and characterization of these viruses increase our knowledge of the geographical distribution, diversity and host range of mosquito-specific bunyaviruses and negeviruses.

Indexed as

AnimalsBunyaviridaeCell LineCulexCytopathogenic Effect, ViralMolecular Sequence DataRNA, ViralSequence Analysis, DNATrinidad and TobagoRNA, Viral

Identifiers

PMID24262627
PMCPMC3917067
OpenAlexW2116009888

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.