ArticlePloS one2013
MicroRNA transcriptome in swine small intestine during weaning stress.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 24 citations in OpenAlex.
- Investigation of salivary microRNAs as non-invasive biomarkers for weaning stress in piglets: A preliminary study.PloS one · 2026Article
- Identification of trait-associated microRNA modules in liver transcriptome of pig fed with PUFAs-enriched supplementary diet.Journal of applied genetics · 2025Article
- Expression Profile of miR-199a and Its Role in the Regulation of Intestinal Inflammation.Animals : an open access journal from MDPI · 2023Article
- Investigation of the Expression Pattern and Functional Role of miR-10b in Intestinal Inflammation.Animals : an open access journal from MDPI · 2023Article
- Genome-Wide Analysis of Long Noncoding RNAs in Porcine Intestine during Weaning Stress.International journal of molecular sciences · 2023Article
- Transcriptomics yields valuable information regarding the response mechanisms of Chinese Min pigs infected with PEDV.Frontiers in veterinary science · 2023Article
- Interplay Between Stress and Reproduction: Novel Epigenetic Markers in Response to Shearing Patterns in Australian Merino Sheep (Frontiers in veterinary science · 2022Article
- MicroRNA expression profiling during the suckling-to-weaning transition in pigs.Journal of animal science and technology · 2021Article
- MicroRNAs as Biomarkers for Animal Health and Welfare in Livestock.Frontiers in veterinary science · 2020Review
- Article
- Identification of endogenous microRNA references in porcine serum for quantitative real-time PCR normalization.Molecular biology reports · 2018Article
- Identification and characterization of microRNAs in the intestinal tissues of sheep (Ovis aries).PloS one · 2018Article
- Over-expression of miR-146b and its regulatory role in intestinal epithelial cell viability, proliferation, and apoptosis in piglets.Biology direct · 2017Article
- Parallel mRNA, proteomics and miRNA expression analysis in cell line models of the intestine.World journal of gastroenterology · 2017Article
- Comprehensive miRNA expression profiles in the ilea of Lawsonia intracellularis-infected pigs.The Journal of veterinary medical science · 2017Article
- Identification of microRNAs regulating Escherichia coli F18 infection in Meishan weaned piglets.Biology direct · 2016Article
- Analysis of Serum microRNA Expression Profiles and Comparison with Small Intestinal microRNA Expression Profiles in Weaned Piglets.PloS one · 2016Article
- Bioinformatic analysis of the ssc-miR-146b upstream promoter region.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2015Article
- Epigenetic marks: regulators of livestock phenotypes and conceivable sources of missing variation in livestock improvement programs.Frontiers in genetics · 2015Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MicroRNAs (miRNAs) play important roles in intestinal diseases; however, the role of miRNAs during weaning stress is unknown. In our study, six jejunal small RNA libraries constructed from weaning piglets at 1, 4 and 7 d after weaning (libraries W1, W4 and W7, respectively) and from suckling piglets on the same days as the weaning piglets (libraries S1, S4 and S7, respectively) were sequenced using Solexa high-throughput sequencing technology. Overall, 260 known swine miRNAs and 317 novel candidate miRNA precursors were detected in the six libraries. The results revealed that 16 differentially expressed miRNAs were found between W1 and S1; 98 differentially expressed miRNAs were found between W4 and S4 (ssc-mir-146b had the largest difference); and 22 differentially expressed miRNAs were found between W7 and S7. Sequencing miRNA results were validated using RT-qPCR. Approximately 11,572 miRNA-mRNA interactions corresponding to 3,979 target genes were predicted. The biological analysis further describe that the differentially expressed miRNAs regulated small intestinal metabolisms, stressful responses and immune functions in piglets. Therefore, the small intestine miRNA transcriptome was significantly different between weaning and suckling piglets; the difference varied with the number of days after weaning.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.