ArticleOncology letters2013
Identification of U251 glioma stem cells and their heterogeneous stem-like phenotypes.
Article in Oncology letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Majusculamide-o, a simplified marine natural product analog, exhibits potent and specific cancer cell cytotoxicity.Scientific reports · 2025Article
- A comprehensive method to analyze single-cell vibrations.Biophysical journal · 2025Article
- Nerve Growth Factor, Antimicrobial Peptides and Chemotherapy: Glioblastoma Combination Therapy to Improve Their Efficacy.Biomedicines · 2023Article
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- Bis-Bibenzyls from the LiverwortPlants (Basel, Switzerland) · 2021Article
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- ΔJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2020Article
- Blockade of the forward NaBritish journal of pharmacology · 2019Article
- R-spodin2 enhances canonical Wnt signaling to maintain the stemness of glioblastoma cells.Cancer cell international · 2018Article
- Research on human glioma stem cells in China.Neural regeneration research · 2017Review
- PNIPAAm-co-JeffamineBiomaterials · 2017Article
- Integrative Network Analysis Combined with Quantitative Phosphoproteomics Reveals Transforming Growth Factor-beta Receptor type-2 (TGFBR2) as a Novel Regulator of Glioblastoma Stem Cell Properties.Molecular & cellular proteomics : MCP · 2016Article
- The PD-1/B7-H1 pathway modulates the natural killer cells versus mouse glioma stem cells.PloS one · 2015Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glioblastoma, the most common and lethal type of intracranial tumor, is characterized by extensive heterogeneity at the cellular and molecular levels. The discovery of glioma stem cells (GSCs) lends support to a new paradigm in tumor biology. In the present study, we aimed to clarify the validity of using U251 glioma cells as a source of GSC culture and critically evaluate the heterogeneous stem-like phenotypes of these cells when grown under various culture conditions. The findings suggested that U251 cells (U251-Adh, U251-SC-Sph and U251-SC-Adh) showed distinctive growth patterns and self-renewal capacity. The U251 glioma cell line is endowed with certain GSC phenotypes that may be moderately enriched
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