Evidence map›Paper›PMID 24256715›Full record

ReviewGut microbes

Efficient responses to host and bacterial signals during Vibrio cholerae colonization.

Francesca P Rothenbacher, Jun Zhu

Open access · bronzeAbstract readReview
In one paragraph

Review in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

  1. Gut microbes · 2026
    Article
  2. Review
  3. Article
  4. Light-activated cAMP signaling controls sodium-driven motility inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Deployment of amBio · 2025
    Article
  6. mBio · 2024
    Article
  7. Article
  8. Article
  9. Deployment of abioRxiv : the preprint server for biology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Virulence Regulation and Innate Host Response in the Pathogenicity ofFrontiers in cellular and infection microbiology · 2020
    Review
  17. Article
  18. The Coli Surface Antigen CS3 of EnterotoxigenicFrontiers in microbiology · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Francesca P RothenbacherDepartment of Microbiology; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA.
Jun ZhuDepartment of Microbiology; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA.
Philadelphia University · US

Funding

Analysis of gene regulation of Vibrio cholerae infectionR01AI072479 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ZHU, JUN · 2007 to 2011
$2.1M
Vibrio cholerae-host interaction at the Intestinal InterfaceR01AI080654 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ZHU, JUN · 2011 to 2014
$1.6M
Defining vibrio cholerae virulence circuitry using bioinformatics and geneticsR21AI088172 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ZHU, JUN · 2010 to 2011
$451k
NIAID NIH HHS R01 AI072479NIAID NIH HHS R01 AI080654NIAID NIH HHS R21 AI 088172NIAID NIH HHS R21 AI088172
6 · The paper itself

Abstract

Vibrio cholerae, the microorganism responsible for the diarrheal disease cholera, is able to sense and respond to a variety of changing stimuli in both its aquatic and human gastrointestinal environments. Here we present a review of research efforts aimed toward understanding the signals this organism senses in the human host. V. cholerae's ability to sense and respond to temperature and pH, bile, osmolarity, oxygen and catabolite levels, nitric oxide, and mucus, as well as the quorum sensing signals produced in response to these factors will be discussed. We also review the known quorum sensing regulatory pathways and discuss their importance with regard to the regulation of virulence and colonization during infection.

Indexed as

Quorum SensingAnimalsBacterial ProteinsCholeraGene Expression Regulation, BacterialHumansVibrio choleraeBacterial Proteinsbilecolonizationenvironmental signalsmucuspHquorum sensingV. choleraevirulence

Identifiers

PMID24256715
PMCPMC4049929
OpenAlexW1967540743

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.