Evidence map›Paper›PMID 24256027›Full record

ArticleJournal of alternative and complementary medicine (New York, N.Y.)2014

Stress reactivity in traditional Chinese medicine-based subgroups of patients with irritable bowel syndrome.

Megan C Chang, David Shapiro, Aditi Joshi, Leila Shahabi, Steven Tan, Suzanne Smith, Ka Kit Hui, Kirsten Tillisch, Emeran A Mayer, Bruce D Naliboff

Abstract read
In one paragraph

Article in Journal of alternative and complementary medicine (New York, N.Y.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Megan C Chang1 Department of Occupational Therapy, San Jose State University , San Jose, CA.
David Shapiro
Aditi Joshi
Leila Shahabi
Steven Tan
Suzanne Smith
Ka Kit Hui
Kirsten Tillisch
Emeran A Mayer
Bruce D Naliboff
University of California, Los Angeles · USSan Jose State University · US

Funding

Women's Health and Functional Visceral Disorders CenterP50DK064539 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MAYER, EMERAN A · 2002 to 2017
$17.5M
Mind/Brain/Body Interactions in Stress-Related DisordersR24AT002681 · NCCIH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MAYER, EMERAN A · 2004 to 2008
$4.6M
Physiologic Characteristics of Traditional Chinese Medicine Based IBS SubgroupsR21AT003221 · NCCIH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI NALIBOFF, BRUCE D · 2006 to 2008
$602k
NCCIH NIH HHS R21 AT003221NCCIH NIH HHS R24 AT002681NIDDK NIH HHS P50 DK64539
6 · The paper itself

Abstract

objectivesThis study aimed to examine differences in autonomic responses to stress, pain perception, and the role of negative affect in these responses in individuals with irritable bowel syndrome (IBS) according to Traditional Chinese Medicine (TCM) classifications.

designFifty-nine female patients with IBS age 18-65 years diagnosed by TCM practitioners as showing primarily an excess (n=32) or an overlap (n=27) pattern (mixed excess and deficiency) were assessed for symptom differences, heart rate, and skin conductance responses to a psychosocial stressor and pain perception. SETTINGS/LOCATIONS: University of California in Los Angeles, California.

resultsCompared with the excess group, the overlap group showed significantly greater overall gastrointestinal symptom severity, abdominal pain, and negative affect. The excess group with higher levels of negative affect showed greater reactivity to stress, whereas the overlap group showed an opposite response pattern. The overlap group showed increased cold sensitivity.

conclusionsIBS patients with the overlap pattern have greater disease severity and comorbidity than those with excess alone. Those with excess showed a pattern of increased stress response with greater negative affect, whereas the overlap group with greater deficiency showed lower physiologic arousal with greater negative affect, consistent with depletion resulting from allostatic load.

Indexed as

AdolescentAdultAgedFemaleGalvanic Skin ResponseHeart RateHumansIrritable Bowel SyndromeLos AngelesMedicine, Chinese TraditionalMiddle AgedStress, PhysiologicalStress, PsychologicalYoung Adult

Identifiers

PMID24256027
PMCPMC3994910
OpenAlexW1518490584

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.