ArticleBiomicrofluidics2013
Electro-entropic excluded volume effects on DNA looping and relaxation in nanochannels.
Article in Biomicrofluidics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Article
- Distribution of label spacings for genome mapping in nanochannels.Biomicrofluidics · 2018Article
- Effects of Polymer Length and Salt Concentration on the Transport of ssDNA in Nanofluidic Channels.Biophysical journal · 2017Article
- Kirkwood diffusivity of long semiflexible chains in nanochannel confinement.Macromolecules · 2015Article
- Stretching of DNA confined in nanochannels with charged walls.Biomicrofluidics · 2014Article
- Probing transient protein-mediated DNA linkages using nanoconfinement.Biomicrofluidics · 2014Article
- Simulations of DNA stretching by flow field in microchannels with complex geometry.Biomicrofluidics · 2014Article
- Erratum: "Electro-entropic excluded volume effects on DNA looping and relaxation in nanochannels" [Biomicrofluidics 7, 054119 (2013)].Biomicrofluidics · 2013Article
Corrections and comments
- Erratum issued
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigate the fluctuation-relaxation dynamics of entropically restricted DNA molecules in square nanochannels ranging from 0.09 to 19.9 times the persistence length. In nanochannels smaller than the persistence length, the chain relaxation time is found to have cubic dependence on the channel size. It is found that the effective polymer width significantly alter the chain conformation and relaxation time in strong confinement. For thinner chains, looped chain configurations are found in channels with height comparable to the persistence length, with very slow relaxation compared to un-looped chains. Larger effective chain widths inhibit the formation of hairpin loops.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.