ReviewMetabolic brain disease2014
Magnetic resonance of the brain in chronic and acute liver failure.
Review in Metabolic brain disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Mitochondrial Changes in Rat Brain Endothelial Cells Associated with Hepatic Encephalopathy: Relation to the Blood-Brain Barrier Dysfunction.Neurochemical research · 2024Review
- Inhibition of urease-mediated ammonia production by 2-octynohydroxamic acid in hepatic encephalopathy.Nature communications · 2024Article
- Neurometabolism and brain morphometry in an adolescent female with an extra-hepatic congenital portosystemic shunt.JPGN reports · 2024Article
- Probiotics improve the neurometabolic profile of rats with chronic cholestatic liver disease.Scientific reports · 2021Article
- Longitudinal osmotic and neurometabolic changes in young rats with chronic cholestatic liver disease.Scientific reports · 2020Article
- Cerebral metabolite alterations in patients with posttransplant encephalopathy after liver transplantation.PloS one · 2019Article
- Hepatic encephalopathy in acute-on-chronic liver failure.Hepatology international · 2015Review
- Pathogenesis of brain edema and investigation into anti-edema drugs.International journal of molecular sciences · 2015Review
- PET and MR imaging of neuroinflammation in hepatic encephalopathy.Metabolic brain disease · 2015Review
- The brain in acute on chronic liver failure.Metabolic brain disease · 2014Review
- Brain Edema in Chronic Hepatic Encephalopathy.Journal of clinical and experimental hepatologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain alterations such as hepatic encephalopathy or brain edema are usually associated with liver failure. The mechanisms that lead to the generation of edema seem to be different depending on the course of liver failure (acute, chronic or acute-on-chronic liver failure). Several neuroimaging methods allow a non-invasive assessment of brain alterations in liver failure. Magnetic resonance has gained more interest due to the ability of giving information about cerebral metabolism using spectroscopy, water distribution by diffusion methods or neuronal connectivity by means of resting state magnetic resonance. These techniques have been applied to experimental models and patients with liver failure to elucidate cerebral pathways involved in the pathogenesis of hepatic encephalopathy. In the future, the development of new magnetic resonance implementations will generate handy tools for the study of the brain and get better understanding of the mechanisms that take place in liver failure. This could be useful for the early diagnosis, as well as for the design of new treatments for cerebral complications of liver failure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.