ReviewEuropean journal of pediatrics2014
Transient leukemia in a newborn without Down syndrome: case report and review of the literature.
Review in European journal of pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- Abnormal heart rate pattern in fetal anaemia secondary to transient abnormal myelopoeisis in a fetus without trisomy 21: A case report.Case reports in women's health · 2023Article
- Rapid next-generation sequencing aids in diagnosis of transient abnormal myelopoiesis in a phenotypically normal newborn.Blood advances · 2022Article
- Transient myeloproliferative disorder as the presenting feature for mosaic trisomy 21.Cold Spring Harbor molecular case studies · 2021Article
- Transient abnormal myelopoiesis in pediatrics with trisomy 21.Clinical case reports · 2021Article
- Donor cell-derived transient abnormal myelopoiesis as a specific complication of umbilical cord blood transplantation.Bone marrow transplantation · 2018Article
- Transient Abnormal Myelopoiesis: A Varied Spectrum of Clinical Presentation.Journal of hematology · 2017Article
- Acute megakaryoblastic leukemia with acquired trisomy 21 and GATA1 mutations in phenotypically normal children.European journal of pediatrics · 2015Review
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledTransient neonatal leukemia occurs almost exclusively in Down syndrome babies. We report here the unusual case of a newborn without Down syndrome who presented neonatal transient leukemia and who achieved spontaneously complete remission. Trisomy 21 and GATA1 mutation were both present in leukemic cells. While close follow-up is advised since true leukemia may develop later, the patient is still in remission for 2.5 years. We performed a literature review of 15 other similar cases.
conclusionOur case of transient leukemia without Down syndrome and the literature review highlight the important role of trisomy 21 and GATA1 mutation in the development of transient neonatal leukemia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.