Evidence map›Paper›PMID 24252561›Full record

ReviewBiotechnology advances

Techniques for physicochemical characterization of nanomaterials.

Ping-Chang Lin, Stephen Lin, Paul C Wang, Rajagopalan Sridhar

Abstract readReview
In one paragraph

Review in Biotechnology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

126 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Physical Changes of Biomacromolecules upon Covalent Surface Immobilization.Langmuir : the ACS journal of surfaces and colloids · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review

66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ping-Chang LinLaboratory of Molecular Imaging, Department of Radiology, Howard University, Washington, DC 20060, USA.
Stephen LinLaboratory of Molecular Imaging, Department of Radiology, Howard University, Washington, DC 20060, USA.
Paul C WangLaboratory of Molecular Imaging, Department of Radiology, Howard University, Washington, DC 20060, USA.
Rajagopalan SridharDepartment of Radiation Oncology, Howard University, Washington, DC 20060, USA. Electronic address: rsridhar@howard.edu.

Funding

PROTEOMICS CORE FACILITYG12MD007597 · NIMHD · HOWARD UNIVERSITY · PI SOUTHERLAND, WILLIAM M. · 2012 to 2018
$14.8M
NIMHD NIH HHS G12 MD007597
6 · The paper itself

Abstract

Advances in nanotechnology have opened up a new era of diagnosis, prevention and treatment of diseases and traumatic injuries. Nanomaterials, including those with potential for clinical applications, possess novel physicochemical properties that have an impact on their physiological interactions, from the molecular level to the systemic level. There is a lack of standardized methodologies or regulatory protocols for detection or characterization of nanomaterials. This review summarizes the techniques that are commonly used to study the size, shape, surface properties, composition, purity and stability of nanomaterials, along with their advantages and disadvantages. At present there are no FDA guidelines that have been developed specifically for nanomaterial based formulations for diagnostic or therapeutic use. There is an urgent need for standardized protocols and procedures for the characterization of nanoparticles, especially those that are intended for use as theranostics.

Indexed as

Chemistry, PhysicalCircular DichroismContrast MediaHumansLightMagnetic Resonance SpectroscopyMass SpectrometryMicroscopy, Atomic ForceMicroscopy, Electron, ScanningMicroscopy, Electron, TransmissionMicroscopy, Scanning TunnelingMolecular ImagingNanomedicineNanoparticlesNanostructuresNanotechnologyContrast MediaImage contrast agentsMolecular imagingNanomedicineNanoparticlePhysicochemical properties

Identifiers

PMID24252561
PMCPMC4024087

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.