ArticleDevelopmental and comparative immunology2014
Colostral antibody-mediated and cell-mediated immunity contributes to innate and antigen-specific immunity in piglets.
Article in Developmental and comparative immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.
- Recent Advances in Camel Immunology.Frontiers in immunology · 2020Pooled it
- Effect of maternal supplementation with seaweed powder on immune status of liver and lymphoid organs of piglets.The Journal of veterinary medical science · 2018Trial
- A randomized controlled study on the efficacy of a novel combination vaccine against enzootic pneumonia (Mycoplasma hyopneumoniae) and porcine Circovirus type 2 (PCV2) in the presence of strong maternally derived PCV2 immunity in pigs.BMC veterinary research · 2017Trial
- Effect of sow vaccination against porcine circovirus type 2 (PCV2) on virological profiles in herds with or without PCV2 systemic disease.The Canadian veterinary journal = La revue veterinaire canadienne · 2016Trial
- Determining the dynamics of maternally derived antibodies in piglets prior to vaccination against porcine circovirus type 2.The Journal of veterinary medical science · 2026Article
- Haematopoietic Traits in Indigenous and Modern Pig Breeds Are Modulated by Housing System and Developmental Stage.Animal genetics · 2026Article
- The narrow window of protection: protective efficacy of maternally derived antibodies against virulent classical swine fever virus in Japan.Veterinary research · 2025Article
- Evaluation of PCV2 vaccine immunogenicity and efficacy using ELISpot to detect virus-specific memory B cells.Porcine health management · 2025Article
- A nanodiamond-formulated plant protein induces robust immunity against porcine epidemic diarrhea virus in piglets.Frontiers in immunology · 2025Article
- Temporal dynamics in the composition of metabolically active bacteria and fungi in the ileo-cecal lymph nodes of suckling and newly weaned piglets.Scientific reports · 2024Article
- Immediate dam-sourced colostrum provision reduces calf mortality - management practices and calf mortality in large dairy herds.Acta veterinaria Scandinavica · 2024Article
- Effects of Dietary Net Energy Concentration on Reproductive Performance, Immune Function, Milk Composition, and Gut Microbiota in Primiparous Lactating Sows.Animals : an open access journal from MDPI · 2024Article
- A field comparison study of two vaccine protocols against Erysipelothrix rhusiopathiae in two types of swine breeds in Spain.BMC veterinary research · 2024Article
- Concentrations of selected immunological parameters in the serum and processing fluid of suckling piglets and the serum and colostrum of their mothers.BMC veterinary research · 2024Article
- Infant respiratory infections modulate lymphocyte homing to breast milk.Frontiers in immunology · 2024Article
- Japanese Encephalitis: Risk of Emergence in the United States and the Resulting Impact.Viruses · 2023Article
- Effects of the Mean Weight of Uniform Litters on Sows and Offspring Performance.Animals : an open access journal from MDPI · 2023Article
- The Effect of Maternal Probiotic or Synbiotic Supplementation on Sow and Offspring Gastrointestinal Microbiota, Health, and Performance.Animals : an open access journal from MDPI · 2023Review
- Testable Candidate Immune Correlates of Protection for Porcine Reproductive and Respiratory Syndrome Virus Vaccination.Vaccines · 2023Review
- Long-term follow-up of Mycoplasma hyopneumoniae-specific immunity in vaccinated pigs.Veterinary research · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Immunoglobulins and immune cells are critical components of colostral immunity; however, their transfer to and function in the neonate, especially maternal lymphocytes, is unclear. Cell-mediated and antibody-mediated immunity in sow blood and colostrum and piglet blood before (PS) and after (AS) suckling were assessed to investigate transfer and function of maternal immunity in the piglet. CD4, CD8, and γδ lymphocytes were found in sow blood and colostrum and piglet blood PS and AS; each had a unique T lymphocyte profile. Immunoglobulins were detected in sow blood, colostrum, and in piglet blood AS; the immunoglobulin profile of piglet serum AS mimicked that of sow serum. These results suggest selectivity in lymphocyte concentration into colostrum and subsequent lymphocyte transfer into the neonate, but that immunoglobulin transfer is unimpeded. Assessment of colostral natural killer activity and antigen-specific proliferation revealed that colostral cells are capable of influencing the innate and specific immune response of neonatal pigs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.