Trial reportContemporary clinical trials2014
The resist diabetes trial: Rationale, design, and methods of a hybrid efficacy/effectiveness intervention trial for resistance training maintenance to improve glucose homeostasis in older prediabetic adults.
Trial report in Contemporary clinical trials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Use of the PRECIS-II instrument to categorize reports along the efficacy-effectiveness spectrum in an hepatitis C virus care continuum systematic review and meta-analysis.Journal of clinical epidemiology · 2018Pooled it
- Resistance training is associated with spontaneous changes in aerobic physical activity but not overall diet quality in adults with prediabetes.Physiology & behavior · 2017Trial
- Resist diabetes: A randomized clinical trial for resistance training maintenance in adults with prediabetes.PloS one · 2017Trial
- The Stepwise Approach to Diabetes Prevention: Results From the D-CLIP Randomized Controlled Trial.Diabetes care · 2016 · on this mapTrial
- Psychosocial mediators of a theory-based resistance training maintenance intervention for prediabetic adults.Psychology & health · 2016Trial
- Prediabetes Phenotype Influences Improvements in Glucose Homeostasis with Resistance Training.PloS one · 2016Trial
- Timing of resistance exercise and cardiometabolic outcomes in adults with prediabetes: a secondary analysis.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- Article
- Physical Fitness Level and Mood State Changes in Basic Military Training.International journal of environmental research and public health · 2020Article
- Adapting the "Resist Diabetes" Resistance Training Intervention for Veterans.Translational journal of the American College of Sports Medicine · 2020Article
- Prevalence of Pre-Diabetes across Ethnicities: A Review of Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT) for Classification of Dysglycaemia.Nutrients · 2017 · on this mapReview
- Voluntary Aerobic Exercise Reverses Frailty in Old Mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2015Article
- Theory-based approach for maintaining resistance training in older adults with prediabetes: adherence, barriers, self-regulation strategies, treatment fidelity, costs.Translational behavioral medicine · 2015Article
- Kidney function, β-cell function and glucose tolerance in older men.The Journal of clinical endocrinology and metabolism · 2015Article
- Using response variation to develop more effective, personalized behavioral medicine?: evidence from the Resist Diabetes study.Translational behavioral medicine · 2014Article
- Dietary intake modification in response to a participation in a resistance training program for sedentary older adults with prediabetes: findings from the Resist Diabetes study.Eating behaviors · 2014Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Advancing age is associated with reduced levels of physical activity, increased body weight and fat, decreased lean body mass, and a high prevalence of type 2 diabetes (T2D). Resistance training (RT) increases muscle strength and lean body mass, and reduces risk of T2D among older adults. The Resist Diabetes trial will determine if a social cognitive theory (SCT)-based intervention improves RT maintenance in older, prediabetic adults, using a hybrid efficacy/effectiveness approach. Sedentary, overweight/obese (BMI: 25-39.9 kg/m(2)) adults aged 50-69 (N = 170) with prediabetes (impaired fasting glucose and/or impaired glucose tolerance) completed a supervised 3-month RT (2×/wk) initiation phase and were then randomly assigned (N = 159; 94% retention) to one of two 6-month maintenance conditions: SCT or standard care. The SCT intervention consisted of faded contacts compared to standard care. Participants continue RT at an approved, self-selected community facility during maintenance. A subsequent 6-month period involves no contact for both conditions. Assessments occur at baseline and months 3 (post-initiation), 9 (post-intervention), and 15 (six months after no contact). Primary outcomes are prediabetes indices (i.e., impaired fasting and 2-hour glucose concentration) and strength. Secondary measures include insulin sensitivity, beta-cell responsiveness, and disposition index (oral glucose and C-peptide minimal model); adherence; body composition; and SCT measures. Resist Diabetes is the first trial to examine the effectiveness of a high fidelity SCT-based intervention for maintaining RT in older adults with prediabetes to improve glucose homeostasis. Successful application of SCT constructs for RT maintenance may support translation of our RT program for diabetes prevention into community settings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.