Evidence map›Paper›PMID 24252262›Full record

ArticleTicks and tick-borne diseases2014

First isolation of the relapsing fever spirochete, Borrelia hermsii, from a domestic dog.

Ashley L Kelly, Sandra J Raffel, Robert J Fischer, Michael Bellinghausen, Connie Stevenson, Tom G Schwan

Abstract readCase Reports
In one paragraph

Article in Ticks and tick-borne diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.1field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 33 citations in OpenAlex.

  1. Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2024
    Article
  2. Article
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  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. ACVIM consensus update on Lyme borreliosis in dogs and cats.Journal of veterinary internal medicine · 2018
    Article
  14. Relapsing Fevers: Neglected Tick-Borne Diseases.Frontiers in cellular and infection microbiology · 2018
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Tick-Borne Relapsing Fever in Dogs.Journal of veterinary internal medicine · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ashley L KellyLaboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4th Street, Hamilton, MT 59840, USA.
Sandra J RaffelLaboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4th Street, Hamilton, MT 59840, USA.
Robert J FischerLaboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4th Street, Hamilton, MT 59840, USA.
Michael BellinghausenKenmore Veterinary Hospital, Kenmore, WA, USA.
Connie StevensonPhoenix Central Laboratories for Veterinarians, Mukilteo, WA, USA.
Tom G SchwanLaboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South 4th Street, Hamilton, MT 59840, USA. Electronic address: tschwan@niaid.nih.gov.
National Institutes of Health · USNational Institute of Allergy and Infectious Diseases · USVeterinarians Without Borders · US

Funding

Adaptations Of Borrelia Spirochetes To Their Tick Vectors And Mammalian HostsZIAAI000492 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI SCHWAN, TOM · 2009 to 2014
$3.3M
Intramural NIH HHS ZIA AI000492
6 · The paper itself

Abstract

In North America, tick-borne relapsing fever of humans is most frequently caused by infection with the spirochete Borrelia hermsii. Prior to our investigation, this spirochete was not known to infect dogs although another species, Borrelia turicatae, has been isolated from domestic canids in Florida and Texas. A clinically ill dog in Washington, USA, was spirochetemic upon examination. Spirochetes were isolated from the dog's serum and examined by PCR and multi-locus sequence typing. DNA sequences for 7 loci all typed the spirochete as B. hermsii and a member of genomic group II of this species. Therefore, companion dogs that reside in rustic cabins in higher elevation forests are at risk of infection with B. hermsii.

Indexed as

AmoxicillinAnimalsAnti-Bacterial AgentsBorreliaDNA, BacterialDNA, Ribosomal SpacerDog DiseasesDogsDoxycyclineFemaleRelapsing FeverAmoxicillinAnti-Bacterial AgentsDNA, BacterialDNA, Ribosomal SpacerDoxycyclineArgasid ticksCanine borreliosisOrnithodoros hermsiRelapsing feverVeterinary pathogens

Identifiers

PMID24252262
PMCPMC3946889
OpenAlexW1974744297

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.