ArticleHPB : the official journal of the International Hepato Pancreato Biliary Association2014
Live liver donors' risk thresholds: risking a life to save a life.
Article in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Perspectives and Tools in Liver Graft Assessment: A Transformative Era in Liver Transplantation.Biomedicines · 2025Review
- Endoscopic treatment of biliary complications in donors after living donor liver transplantation in a high volume transplant center.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020Article
- Predicting chance of liver transplantation for pediatric wait-list candidates.Pediatric transplantation · 2019Article
- Complement Therapeutics in the Multi-Organ Donor: Do or Don't?Frontiers in immunology · 2019Review
- Live liver donors' information needs: A qualitative study of practical implications for informed consent.Surgery · 2016Article
- Donor Evaluation Protocol for Live and Deceased Donors.Journal of clinical and experimental hepatologyReview
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is still some controversy regarding the ethical issues involved in live donor liver transplantation (LDLT) and there is uncertainty on the range of perioperative morbidity and mortality risks that donors will consider acceptable.
methodsThis study analysed donors' inclinations towards LDLT using decision analysis techniques based on the probability trade-off (PTO) method. Adult individuals with an emotional or biological relationship with a patient affected by end-stage liver disease were enrolled. Of 122 potential candidates, 100 were included in this study.
resultsThe vast majority of participants (93%) supported LDLT. The most important factor influencing participants' decisions was their wish to improve the recipient's chance of living a longer life. Participants chose to become donors if the recipient was required to wait longer than a mean ± standard deviation (SD) of 6 ± 5 months for a cadaveric graft, if the mean ± SD probability of survival was at least 46 ± 30% at 1 month and at least 36 ± 29% at 1 year, and if the recipient's life could be prolonged for a mean ± SD of at least 11 ± 22 months.
conclusionsPotential donors were risk takers and were willing to donate when given the opportunity. They accepted significant risks, especially if they had a close emotional relationship with the recipient.
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