ArticleThe European journal of neuroscience2014
Noise-rearing disrupts the maturation of multisensory integration.
Article in The European journal of neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 44 citations in OpenAlex.
- A neuro-computational framework for modeling the development of cross-sensory interactions in Autism: from mechanistic understanding to targeted intervention.Research square · 2026Article
- The reliability of multisensory integration in enhancing behavioral performance.Neuroscience and biobehavioral reviews · 2026Review
- Unraveling Audiovisual Perception Across Space and Time: A Neuroinspired Computational Architecture.The European journal of neuroscience · 2025Article
- Is Competition the Default Configuration of Cross-Sensory Interactions?The European journal of neuroscience · 2025Article
- The brain can develop conflicting multisensory principles to guide behavior.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- The Development of Multisensory Integration at the Neuronal Level.Advances in experimental medicine and biology · 2024Article
- Development of multisensory processing in ferret parietal cortex.The European journal of neuroscience · 2023Article
- Noise-rearing precludes the behavioral benefits of multisensory integration.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Crossmodal interactions in human learning and memory.Frontiers in human neuroscience · 2023Review
- Atypical development of causal inference in autism inferred through a neurocomputational model.Frontiers in computational neuroscience · 2023Article
- Article
- Resolution of impaired multisensory processing in autism and the cost of switching sensory modality.Communications biology · 2022Article
- Neuroplasticity and Crossmodal Connectivity in the Normal, Healthy Brain.Psychology & neuroscience · 2021Article
- Multisensory enhancement of overt behavior requires multisensory experience.The European journal of neuroscience · 2021Article
- Stimulus value gates multisensory integration.The European journal of neuroscience · 2021Article
- Using superior colliculus principles of multisensory integration to reverse hemianopia.Neuropsychologia · 2020Article
- Experience Creates the Multisensory Transform in the Superior Colliculus.Frontiers in integrative neuroscience · 2020Article
- Cross-Modal Competition: The Default Computation for Multisensory Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Development of the Mechanisms Governing Midbrain Multisensory Integration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- The normal environment delays the development of multisensory integration.Scientific reports · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
It is commonly believed that the ability to integrate information from different senses develops according to associative learning principles as neurons acquire experience with co-active cross-modal inputs. However, previous studies have not distinguished between requirements for co-activation versus co-variation. To determine whether cross-modal co-activation is sufficient for this purpose in visual-auditory superior colliculus (SC) neurons, animals were reared in constant omnidirectional noise. By masking most spatiotemporally discrete auditory experiences, the noise created a sensory landscape that decoupled stimulus co-activation and co-variance. Although a near-normal complement of visual-auditory SC neurons developed, the vast majority could not engage in multisensory integration, revealing that visual-auditory co-activation was insufficient for this purpose. That experience with co-varying stimuli is required for multisensory maturation is consistent with the role of the SC in detecting and locating biologically significant events, but it also seems likely that this is a general requirement for multisensory maturation throughout the brain.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.