ArticleIranian journal of neurology2013
The effect of body fat mass and fat free mass on migraine headache.
Article in Iranian journal of neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Smoking in primary headaches - a systematic review and meta-analysis.The journal of headache and pain · 2025Pooled it
- The Role of Diet and Nutrition in Migraine Triggers and Treatment: A Systematic Literature Review.Headache · 2020Pooled it
- The Effect of Bariatric Surgery on Migraines: a Systematic Review and Meta-analysis.Obesity surgery · 2020Pooled it
- Migraine and body mass index categories: a systematic review and meta-analysis of observational studies.The journal of headache and pain · 2015Pooled it
- Bariatric Surgery Promising in Migraine Control: a Controlled Trial on Weight Loss and Its Effect on Migraine Headache.Obesity surgery · 2018Trial
- Migraine management: Non-pharmacological points for patients and health care professionals.Open medicine (Warsaw, Poland) · 2022Review
- Implication of High Body Fat Percentage on Migraine Chronification in Premenopausal Females.Neurology research international · 2022Article
- Applications of Ketogenic Diets in Patients with Headache: Clinical Recommendations.Nutrients · 2021Review
- Association of diet and headache.The journal of headache and pain · 2019Review
- Prevalence of new-onset migraine in patients with idiopathic intracranial hypertension in comparison to the general population.Iranian journal of neurology · 2018Article
- The serum level of inflammatory markers in chronic and episodic migraine: a case-control study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2018Article
- Association of Helicobacter pylori antibodies and severity of migraine attack.Iranian journal of neurology · 2015Article
- Fasting lipid and lipoproteins concentrations in pregnant women with a history of migraine.Headache · 2015Article
- Migraine and type 2 diabetes; is there any association?Journal of diabetes and metabolic disorders · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity seems to be associated to migraine headache. Increase in body fat, especially in gluteofemoral region, elevates adiponectin and leptin secretion which in turn impair inflammatory processes that could be contributing to migraine risk. This study was designed to assess the relationship between body composition and risk of migraine for the first time.
methodsIn this cross-sectional study, 1510 middle-aged women who were visited in a weight reduction clinic of university were recruited. Migraine was diagnosed with HIS criteria. Body composition parameters including total fat mass (FATM), total fat free mass (FFM), truncal fat mass (TFATM), and truncal fat free mass (TFFM) was assessed using bioelectric impedance. We further assessed cardiovascular risk factors and smoking as confounding factors. To determine the real association between different variables and risk of migraine, the associations were adjusted by multivariate logistic regression analysis.
resultsElevation in fasting blood sugar, total cholesterol, LDL cholesterol, FFM, TFFM, and waist-to-hip ratio increased the risk of migraine. When the associations were adjusted for other factors, only the association between migraine and FFM remained statistically significant.
conclusionLower FFM increased the risk of migraine in overweight and obese individuals. In the other words, higher fat free mass could be a protective factor for migraine.
Indexed as
Identifiers
24250893PMC3829270W1602021272What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.