Trial reportAfrican health sciences2013
Impact of weight loss on markers of systemic inflammation in obese Saudi children with asthma.
Trial report in African health sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Clinical Outcomes Following Exercise Rehabilitation in People with Multimorbidity: A Systematic Review.Journal of rehabilitation medicine · 2023Pooled it
- Weight Loss for Children and Adults with Obesity and Asthma. A Systematic Review of Randomized Controlled Trials.Annals of the American Thoracic Society · 2019Pooled it
- Trial
- A Multifactorial Weight Reduction Programme for Children with Overweight and Asthma: A Randomized Controlled Trial.PloS one · 2016Trial
- Management of the pediatric patient with asthma and obesity.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024Review
- Physical Activity as a Modern Intervention in the Fight against Obesity-Related Inflammation in Type 2 Diabetes Mellitus and Gestational Diabetes.Antioxidants (Basel, Switzerland) · 2023Review
- Predictive and prognostic value of leptin status in asthma.NPJ primary care respiratory medicine · 2023Article
- Feasibility of exercise therapy for children with asthma: a meta-analysis.Frontiers in cell and developmental biology · 2023Article
- The Impact of Dietary Intervention in Obese Children on Asthma Prevention and Control.Nutrients · 2022Review
- Adiponectin and Asthma: Knowns, Unknowns and Controversies.International journal of molecular sciences · 2021Review
- The impact of obesity on immune function in pediatric asthma.Current opinion in allergy and clinical immunology · 2021Review
- Exercise and lifestyle changes in pediatric asthma.Current opinion in pulmonary medicine · 2020Review
- Association of pediatric obesity and asthma, pulmonary physiology, metabolic dysregulation, and atopy; and the role of weight management.Expert review of endocrinology & metabolism · 2019Review
- Effects of Telephone Follow-Up Intervention on %Body Fat, Inflammatory Cytokines, and Oxidative Stress in Obese Hispanic Children.International journal of environmental research and public health · 2019Article
- Behavioral trials in the Arab Gulf States: A scoping review.SAGE open medicine · 2019Article
- A Behavioral Family Intervention for Children with Overweight and Asthma.Clinical practice in pediatric psychology · 2018Article
- Four Months of a School-Based Exercise Program Improved Aerobic Fitness and Clinical Outcomes in a Low-SES Population of Normal Weight and Overweight/Obese Children With Asthma.Frontiers in pediatrics · 2018Article
- The metabolic syndrome and chronic kidney disease.Translational research : the journal of laboratory and clinical medicine · 2017Review
- Obesity, Asthma, and Exercise in Child and Adolescent Health.Pediatric exercise science · 2016Article
- Bronchial asthma and chronic obstructive pulmonary disease: research activity in Arab countries.Multidisciplinary respiratory medicine · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWeight loss studies were conducted in children without asthma have demonstrated a reduction in systemic inflammation. However, the impact of weight loss in the obese paediatric population with asthma has not been investigated.
objectiveTo measure the effects of weight loss on markers of systemic inflammation in obese children with bronchial asthma.
methodsEighty obese children with bronchial asthma (42 boys, and 38 girls) with mean age 13.86 ± 3.21 years were divided into two equal groups. The training group received diet regimen, exercise training in addition to the medical treatment for two months, where the control group received the medical treatment only.
resultsThere was a 17.5%, 15.5%, 22.4%, 14.1% and 15.9% reduction in mean values of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), interleukin-8 (IL-8), Leptin and body mass index (BMI) respectively and 38.7 % increase in mean values of adiponectin in the training group. While, there was a 0.7%, 9.0%, 2.8%, 1.6% and 1.2% increase in mean values of TNF-alpha, IL-6, IL-8, Leptin and BMI respectively and 3.9% decrease in mean values of adiponectin in the control group. The mean values of TNF-alpha, IL-6, IL-8, Leptin and BMI was decreased and adiponectin was increased significantly in the training group, however the results of the control group were not significant. Also, there were significant differences between both groups at the end of the study.
conclusionWeight loss improves markers of systemic inflammation in obese Saudi children with bronchial asthma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.