ArticleTheScientificWorldJournal2013
In vitro susceptibility of Candida species to four antifungal agents assessed by the reference broth microdilution method.
Article in TheScientificWorldJournal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Global prevalence and trends of fluconazole resistance in non-albicans Candida species: a systematic review and meta-analysis.BMC infectious diseases · 2026Pooled it
- Twenty-Year Course of Antifungal Resistance inJournal of fungi (Basel, Switzerland) · 2025Review
- High-Throughput Monitoring of Pathogenic Fungal Growth Using Whole Slide Imaging for Rapid Antifungal Susceptibility Assessment.Analytical letters · 2024Article
- Evaluation of antifungal effect of amphotericin B in comparison with nystatin on Candida species derived from patients undergoing head-and-neck radiotherapy.Dental research journal · 2024Article
- High value valorization of lignin as environmental benign antimicrobial.Materials today. Bio · 2023Review
- Article
- The newly synthesized thiazole derivatives as potential antifungal compounds against Candida albicans.Applied microbiology and biotechnology · 2021Article
- Assessing the Bioactive Profile of Antifungal-Loaded Calcium Sulfate against Fungal Biofilms.Antimicrobial agents and chemotherapy · 2021Article
- Prevalence and antifungal susceptibility of Candida albicans causing vaginal discharge among pregnant women in Lebanon.BMC infectious diseases · 2020Article
- Surfactin Like Broad Spectrum Antimicrobial Lipopeptide Co-produced With Sublancin FromFrontiers in microbiology · 2020Article
- In vitro activity of four triazole antifungal drugs against clinically common and uncommon yeast species.Current medical mycology · 2019Article
- The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2019Article
- Rice Defensin OsAFP1 is a New Drug Candidate against Human Pathogenic Fungi.Scientific reports · 2018Article
- Article
- Antifungal Susceptibility and Risk Factors in Patients with Candidemia.The Eurasian journal of medicine · 2016Article
- Identification and antifungal susceptibility of Candida species isolated from bloodstream infections in Konya, Turkey.Annals of clinical microbiology and antimicrobials · 2016Article
- The influence of tea tree oil (Melaleuca alternifolia) on fluconazole activity against fluconazole-resistant Candida albicans strains.BioMed research international · 2015Article
- Primary or secondary antifungal prophylaxis in patients with hematological maligancies: efficacy and damage.Therapeutics and clinical risk management · 2014Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study was performed to determine the distribution of Candida species isolated from the blood cultures of the patients hospitalized in our hospital and to investigate their antifungal susceptibility. Candida strains were identified at species level by using classical methods and API ID 32C (bioMerieux, France) identification kits. The susceptibility of the strains to amphotericin B, fluconazole, voriconazole, and caspofungin was evaluated by using the reference broth microdilution method in document M27-A3 of the Clinical and Laboratory Standards Institute. Of the 111 Candida strains isolated, 47.7% were identified as C. albicans and 52.3% as non-albicans Candida strains. The MIC ranges were 0.03-1 μg/mL for amphotericin B, 0.125-≥64 μg/mL for fluconazole, 0.03-16 μg/mL for voriconazole, and 0.015-0.25 μg/mL for caspofungin. All Candida strains were susceptible to amphotericin B and caspofungin. 10.8% isolates were resistant to fluconazole and 8.1% isolates were dose-dependent susceptible. While 0.9% isolate was resistant to voriconazole, 0.9% isolate was dose-dependent susceptible. In our study, C. albicans and C. parapsilosis were the most frequently encountered agents of candidemia and it was detected that voriconazole with a low resistance rate might also be used with confidence in the treatment of infections occurring with these agents, primarily besides amphotericin B and caspofungin.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.