ArticleJournal of oral and maxillofacial pathology : JOMFP2013
HPV involvement in OSCC: Correlation of PCR results with light microscopic features.
Article in Journal of oral and maxillofacial pathology : JOMFP, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Impact of the COVID-19 Pandemic on Pathological Stage, Tumor Characteristics and Surgical Outcomes of Oral Squamous Cell Carcinoma: A Retrospective Analysis.Medicina (Kaunas, Lithuania) · 2025Article
- Article
- [Effect of risk factor control policies on oral cancer mortality in Latin America].Revista espanola de salud publica · 2019Article
- Benign proliferative epithelial lesions of oral mucosa are infrequently associated with α-, β-, or γ human papillomaviruses.Laryngoscope investigative otolaryngology · 2019Article
- Silencing of LINC01116 suppresses the development of oral squamous cell carcinoma by up-regulating microRNA-136 to inhibit FN1.Cancer management and research · 2019Article
- A Comparative Immunohistochemical Study of Presence and Distribution Pattern of Stromal Myofibroblast in Oral Dysplasia and in Different Grades of Oral Squamous Cell Carcinoma.Journal of International Society of Preventive & Community DentistryArticle
- Detection of human papilloma virus-E6/E7 proteins of high-risk human papilloma virus in saliva and lesional tissue of oral squamous cell carcinoma patients using nested multiplex polymerase chain reaction: A comparative study.Journal of oral and maxillofacial pathology : JOMFPArticle
- Assessment of human papilloma virus as an independent risk factor in non-habituated oral tongue squamous cell carcinoma patients - An institutional study.Journal of oral and maxillofacial pathology : JOMFPArticle
- Prevalence of human papillomavirus16 DNA and p16Journal of oral and maxillofacial pathology : JOMFPArticle
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Authors and funding
6 authors.
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Abstract
objectivesThe study evaluated pathognomic histopathological features with the help of light microscopy for detecting the integration of human papillomavirus (HPV) (type 16 and 18) in oral squamous cell carcinoma (OSCC). MATERIALS AND
methodsForty-five histopathologically diagnosed cases of OSCC were evaluated for the presence of E6/E7 protein of HPV (16 + 18) with the help of nested multiplex polymerase chain reaction. Both HPV-positive and -negative cases were evaluated for four histological features: Koilocytes, dyskeratosis, invasion, and alteration of collagen.
resultsFischer's exact test showed significant difference (P < 0.01%) for the presence of koilocytes and dyskeratosis, whereas no difference was observed for invasion and alteration in collagen between HPV-positive and -negative OSCC.
conclusionThe presence of koilocytes and dyskeratosis at light microscopic level can be used as a marker for the presence of HPV (type 16 and 18) in OSCC.
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