ReviewClinical rheumatology2014
Can traumatic injury trigger psoriatic arthritis? A review of the literature.
Review in Clinical rheumatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Psoriatic arthritis and physical activity: a systematic review.Clinical rheumatology · 2021Pooled it
- The obesity-inflammation axis in psoriatic disease: mechanisms and therapeutic strategies.Nature reviews. Rheumatology · 2026Review
- Environmental and occupational contributors to autoimmune, inflammatory, and musculoskeletal rheumatic disease: a review of emerging evidence and clinical implications.Current opinion in rheumatology · 2026Review
- Differential joint-level response to secukinumab in psoriatic arthritis: A collaborative European observational cohort study.EULAR rheumatology open · 2025Article
- Risk prediction model for psoriatic arthritis: NHANES data and multi-algorithm approach.Clinical rheumatology · 2025Article
- The Role of Epigenetic Factors in the Pathogenesis of Psoriasis.International journal of molecular sciences · 2024Review
- C1-C2 subluxation in enthesitis-related arthritis: two case reports and literature review of ten cases.Pediatric rheumatology online journal · 2023Review
- The Conundrum of Psoriatic Arthritis: a Pathogenetic and Clinical Pattern at the Midpoint of Autoinflammation and Autoimmunity.Clinical reviews in allergy & immunology · 2023Review
- Phenotypic heterogeneity in psoriatic arthritis: towards tissue pathology-based therapy.Nature reviews. Rheumatology · 2023Review
- Janus Kinase Inhibitors: A New Tool for the Treatment of Axial Spondyloarthritis.International journal of molecular sciences · 2023Review
- A review of JAK-STAT signalling in the pathogenesis of spondyloarthritis and the role of JAK inhibition.Rheumatology (Oxford, England) · 2022Review
- Quality of life and its relation to periarticular bone changes in psoriatic patients with or without joint involvement.Clinical rheumatology · 2021Article
- Characteristics of Post-traumatic-spondyloarthritis: A Cross-sectional Study From a Single Tertiary Hospital.Journal of rheumatic diseases · 2021Article
- The ultrasonographic study of the nail reveals differences in patients affected by inflammatory and degenerative conditions.Clinical rheumatology · 2019Article
- Preventing psoriatic arthritis: focusing on patients with psoriasis at increased risk of transition.Nature reviews. Rheumatology · 2019Review
- The role of epigenetics and immunological imbalance in the etiopathogenesis of psoriasis and psoriatic arthritis.Therapeutic advances in musculoskeletal disease · 2019Review
- Inflammatory Joint Disorders and Neutrophilic Dermatoses: a Comprehensive Review.Clinical reviews in allergy & immunology · 2018Review
- Post-traumatic arthritis: overview on pathogenic mechanisms and role of inflammation.RMD open · 2016Review
- The Epidemiology of Psoriatic Arthritis.Rheumatic diseases clinics of North America · 2015Review
- The microbiome and psoriatic arthritis.Current rheumatology reports · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traumatic injury as a trigger for the subsequent development of psoriatic arthritis (PsA) has been implicated by several case reports and case series. However, it is still unclear whether trauma is the inciting event or just an incidental finding. It is thought that the interplay of genetic, immunologic, and environmental factors, such as trauma, may trigger the development of PsA. At least two hypotheses of how trauma may be linked to the development of PsA have surfaced and involve a "deep Koebner effect," the concept of a synovio-entheseal complex and activation of the innate immune system by biomechanical factors. The role of neuropeptides such as substance P and vasoactive intestinal peptide has been highlighted in the synovium after trauma. Better understanding of this phenomenon would shed light into the pathophysiology of Psa and help the development of preventive and therapeutic strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.