Evidence map›Paper›PMID 24248674›Full record

ArticleAIDS and behavior2014

"Set it and forget it": women's perceptions and opinions of long-acting topical vaginal gels.

Jacob J van den Berg, Rochelle K Rosen, Dana E Bregman, Lara A Thompson, Kathleen M Jensen, Patrick F Kiser, David F Katz, Karen Buckheit, Robert W Buckheit, Kathleen M Morrow

Abstract read
In one paragraph

Article in AIDS and behavior, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
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  12. Achieving the optimal vaginal state: using vaginal products and study gels in Uganda, Zimbabwe, and South Africa.International journal of sexual health : official journal of the World Association for Sexual Health · 2017
    Article
  13. Article
  14. Article
  15. Article
  16. Vaginal drug distribution modeling.Advanced drug delivery reviews · 2015
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jacob J van den BergCenters for Behavioral and Preventive Medicine, The Miriam Hospital, Providence, RI, USA, jacob_vandenberg@brown.edu.
Rochelle K Rosen
Dana E Bregman
Lara A Thompson
Kathleen M Jensen
Patrick F Kiser
David F Katz
Karen Buckheit
Robert W Buckheit
Kathleen M Morrow

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI LARRY K BROWN · 1998 to 2026
$51.7M
Preclinical User Accptability Studies Long Acting Vaginal Gels, Intravaginal RingU19AI077289 · NIAID · IMQUEST BIOSCIENCES · PI KISER, PATRICK FRANKLIN · 2008 to 2012
$6.7M
Advancing Reproductive Health: Qualitative Methods & Interdisciplinary MentorshipK24HD062645 · NICHD · MIRIAM HOSPITAL · PI GUTHRIE, KATE M · 2012 to 2016
$689k
NIAID NIH HHS P30 AI042853NIAID NIH HHS U19 AI077289NICHD NIH HHS K24 HD062645
6 · The paper itself

Abstract

Women's initial understandings and anticipated acceptability of long-acting vaginal gels as potential anti-HIV microbicides was investigated by exploring the perceptibility variables associated with prototype formulations. Four focus groups with 29 women, aged 18-45, were conducted to consider gel prototypes with varied physicochemical and rheological properties. Participants responded favorably to the concept of long-acting vaginal gels as microbicides. Distinctions in understandings and stated needs regarding product dosing, characteristics, and effectiveness offer valuable insights into product design. Long-acting vaginal gels capable of protecting against HIV/STIs will be a viable option among potential users, with dosing frequency being an important factor in willingness to use.

Indexed as

Administration, IntravaginalAdolescentAdultAnti-Infective Agents, LocalFemaleFocus GroupsHIV InfectionsHumansInterviews as TopicPatient Acceptance of Health CarePerceptionQualitative ResearchSexually Transmitted DiseasesTime FactorsVaginal Creams, Foams, and JelliesAnti-Infective Agents, LocalVaginal Creams, Foams, and Jellies

Identifiers

PMID24248674
PMCPMC4018755

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.