ArticleProceedings of the National Academy of Sciences of the United States of America2013
Copper control of bacterial nitrous oxide emission and its impact on vitamin B12-dependent metabolism.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed, 148 citations in OpenAlex.
- A novelApplied and environmental microbiology · 2026Article
- Incomplete denitrifying bacteria drive N2O fluxes in ancient Siberian permafrost microcosms.FEMS microbiology ecology · 2026Article
- Article
- Microbe Profile:Microbiology (Reading, England) · 2026Review
- Recent progress in microbial production and consumption of nitrous oxide in agricultural soils.World journal of microbiology & biotechnology · 2025Review
- Review
- Metabolic labour division trade-offs in denitrifying microbiomes.The ISME journal · 2025Review
- Selective enrichment of high-affinity clade II NISME communications · 2025Article
- H-NOX Influences Biofilm Formation, Central Metabolism, and Quorum Sensing inJournal of proteome research · 2024Article
- Unraveling the genetic potential of nitrous oxide reduction in wastewater treatment: insights from metagenome-assembled genomes.Applied and environmental microbiology · 2024Article
- Sustained bacterial NNature communications · 2024Article
- Genomic and environmental controls on Castellaniella biogeography in an anthropogenically disturbed subsurface.Environmental microbiome · 2024Article
- Choline degradation inJournal of bacteriology · 2024Article
- pH selects for distinct NISME communications · 2024Article
- Quest for Nitrous Oxide-reducing Bacteria Present in an Anammox Biofilm Fed with Nitrous Oxide.Microbes and environments · 2024Article
- Copper pyrazole addition regulates soil mineral nitrogen turnover by mediating microbial traits.Frontiers in microbiology · 2024Article
- DksA, ppGpp, and RegAB Regulate Nitrate Respiration in Paracoccus denitrificans.Journal of bacteriology · 2023Article
- Inhibition of Methylmercury and Methane Formation by Nitrous Oxide in Arctic Tundra Soil Microcosms.Environmental science & technology · 2023Article
- Consumption of NMicroorganisms · 2022Article
- The Di-Iron Protein YtfE Is a Nitric Oxide-Generating Nitrite Reductase Involved in the Management of Nitrosative Stress.Journal of the American Chemical Society · 2022Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Global agricultural emissions of the greenhouse gas nitrous oxide (N2O) have increased by around 20% over the last 100 y, but regulation of these emissions and their impact on bacterial cellular metabolism are poorly understood. Denitrifying bacteria convert nitrate in soils to inert di-nitrogen gas (N2) via N2O and the biochemistry of this process has been studied extensively in Paracoccus denitrificans. Here we demonstrate that expression of the gene encoding the nitrous oxide reductase (NosZ), which converts N2O to N2, is regulated in response to the extracellular copper concentration. We show that elevated levels of N2O released as a consequence of decreased cellular NosZ activity lead to the bacterium switching from vitamin B12-dependent to vitamin B12-independent biosynthetic pathways, through the transcriptional modulation of genes controlled by vitamin B12 riboswitches. This inhibitory effect of N2O can be rescued by addition of exogenous vitamin B12.
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