Evidence map›Paper›PMID 24248356›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2013

Quantifying causal emergence shows that macro can beat micro.

Erik P Hoel, Larissa Albantakis, Giulio Tononi

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers.

0numbers the graph read from it
0cells of the map it votes in
118citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

118 citing papers in PubMed.

  1. Review
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  4. Causal graph neural networks for healthcare.Nature biomedical engineering · 2026
    Review
  5. Article
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  13. A reframed landscape of causal emergence.Patterns (New York, N.Y.) · 2026
    Article
  14. Quantifying emergent complexity.Patterns (New York, N.Y.) · 2026
    Article
  15. Intrinsic units: identifying a system's causal grain.Neuroscience of consciousness · 2026
    Article
  16. Article
  17. Article
  18. Whole-to-parts causation mechanism.Frontiers in psychology · 2026
    Article
  19. Article
  20. Article

58 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Erik P HoelDepartment of Psychiatry, University of Wisconsin, Madison, WI 53719.
Larissa Albantakis
Giulio Tononi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Causal interactions within complex systems can be analyzed at multiple spatial and temporal scales. For example, the brain can be analyzed at the level of neurons, neuronal groups, and areas, over tens, hundreds, or thousands of milliseconds. It is widely assumed that, once a micro level is fixed, macro levels are fixed too, a relation called supervenience. It is also assumed that, although macro descriptions may be convenient, only the micro level is causally complete, because it includes every detail, thus leaving no room for causation at the macro level. However, this assumption can only be evaluated under a proper measure of causation. Here, we use a measure [effective information (EI)] that depends on both the effectiveness of a system's mechanisms and the size of its state space: EI is higher the more the mechanisms constrain the system's possible past and future states. By measuring EI at micro and macro levels in simple systems whose micro mechanisms are fixed, we show that for certain causal architectures EI can peak at a macro level in space and/or time. This happens when coarse-grained macro mechanisms are more effective (more deterministic and/or less degenerate) than the underlying micro mechanisms, to an extent that overcomes the smaller state space. Thus, although the macro level supervenes upon the micro, it can supersede it causally, leading to genuine causal emergence--the gain in EI when moving from a micro to a macro level of analysis.

Indexed as

Information TheoryModels, TheoreticalComputer SimulationSystems Biology

Identifiers

PMID24248356
PMCPMC3856819

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.