ArticleBiology open2013
High plasticity in epithelial morphogenesis during insect dorsal closure.
Article in Biology open, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 43 citations in OpenAlex.
- Defense of locust eggs against Metarhizium anisopliae invasion.Pest management science · 2026Article
- Long-term fluorescence live imaging of honeybee embryos using light sheet fluorescence microscopy and halocarbon-based liquids.Biology open · 2025Article
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- The Enigmas of Tissue Closure: Inspiration fromCurrent issues in molecular biology · 2024Review
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- A two-level staging system for the embryonic morphogenesis of the Mediterranean fruit fly (medfly) Ceratitis capitata.PloS one · 2024Article
- How two extraembryonic epithelia became one: serosa and amnion features and functions ofPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Persistent Parental RNAi in the BeetleAdvanced genetics (Hoboken, N.J.) · 2022Article
- Co-option of stress mechanisms in the origin of evolutionary novelties.Evolution; international journal of organic evolution · 2022Article
- Unexpected mutual regulation underlies paralogue functional diversification and promotes epithelial tissue maturation in Tribolium.Communications biology · 2020Article
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- Two consecutive microtubule-based epithelial seaming events mediate dorsal closure in the scuttle flyeLife · 2018Article
- Evolution and multiple roles of the Pancrustacea specific transcription factor zelda in insects.PLoS genetics · 2017Article
- Light Sheet-based Fluorescence Microscopy of Living or Fixed and Stained Tribolium castaneum Embryos.Journal of visualized experiments : JoVE · 2017Article
- TheFrontiers in zoology · 2017Article
- Article
- Live imaging of Tribolium castaneum embryonic development using light-sheet-based fluorescence microscopy.Nature protocols · 2015Article
- The iBeetle large-scale RNAi screen reveals gene functions for insect development and physiology.Nature communications · 2015Article
- Evolution of epithelial morphogenesis: phenotypic integration across multiple levels of biological organization.Frontiers in genetics · 2015Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Insect embryos complete the outer form of the body via dorsal closure (DC) of the epidermal flanks, replacing the transient extraembryonic (EE) tissue. Cell shape changes and morphogenetic behavior are well characterized for DC in Drosophila, but these data represent a single species with a secondarily reduced EE component (the amnioserosa) that is not representative across the insects. Here, we examine DC in the red flour beetle, Tribolium castaneum, providing the first detailed, functional analysis of DC in an insect with complete EE tissues (distinct amnion and serosa). Surprisingly, we find that differences between Drosophila and Tribolium DC are not restricted to the EE tissue, but also encompass the dorsal epidermis, which differs in cellular architecture and method of final closure (zippering). We then experimentally manipulated EE tissue complement via RNAi for Tc-zen1, allowing us to eliminate the serosa and still examine viable DC in a system with a single EE tissue (the amnion). We find that the EE domain is particularly plastic in morphogenetic behavior and tissue structure. In contrast, embryonic features and overall kinetics are robust to Tc-zen1(RNAi) manipulation in Tribolium and conserved with a more distantly related insect, but remain substantially different from Drosophila. Although correct DC is essential, plasticity and regulative, compensatory capacity have permitted DC to evolve within the insects. Thus, DC does not represent a strong developmental constraint on the nature of EE development, a property that may have contributed to the reduction of the EE component in the fly lineage.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.