ReviewPLoS neglected tropical diseases2013
Understanding the persistence of plague foci in Madagascar.
Review in PLoS neglected tropical diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04688996 (Point of Care Diagnostic to Identify the Causative Agent of the Plague in Blood Samples), which is not on this map. Cited by 91 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Point of Care Diagnostic to Identify the Causative Agent of the Plague in Blood Samples
Who cites it
91 citing papers in PubMed, 194 citations in OpenAlex.
- The flea Xenopsylla brasiliensis in Madagascar: updated distribution, host interactions, and initial assessment of insecticide susceptibility.Scientific reports · 2026Article
- Emergence, global dispersal, and local adaptations ofApplied and environmental microbiology · 2026Review
- Article
- Environmental changes and risk of plague epidemics in Indonesia.PLoS neglected tropical diseases · 2025Review
- Evaluating the early diversification of Yersinia pestis and its phylogeographic expansion over 96 years of evolution in Madagascar.Communications biology · 2025Article
- Interaction of Bacteria and Fleas, Focusing on the Plague Bacterium-A Review.Microorganisms · 2025Review
- First assessment of plague in terrestrial small mammals and fleas from Makira Natural Park and surroundings, North-eastern Madagascar.PLoS neglected tropical diseases · 2025Article
- Bioecology of fleas with a focus on the plague vector Xenopsylla Brasiliensis in Mandritsara district, Northern Madagascar.Scientific reports · 2025Article
- Development and evaluation of a triplex real-time PCR assay for enhanced plague diagnostics in Madagascar.PLoS neglected tropical diseases · 2025Article
- Unraveling the role of rat and flea population dynamics on the seasonality of plague epidemics in Madagascar.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Community-led intensive trapping reduces abundance of key plague reservoir and flea vector.Tropical medicine and health · 2025Article
- Opportunities and challenges for plague vector control in Madagascar.PLoS neglected tropical diseases · 2025Review
- Malagasy flea microbiota results from a combination of vertically transmitted and environmentally acquired microbes.Scientific reports · 2025Article
- Confronting cultures: northern Madagascar's cultural beliefs and the relationship of owls and humans.BMC ecology and evolution · 2025Article
- Madagascar's Plague: One Health Research Aims to Slow Its Spread.Environmental health perspectives · 2024Article
- Impact of Sanitation on Rodent Pullulation and Plague Status in an Informal Settlement on the Outskirts of Mahajanga (Madagascar).Pathogens (Basel, Switzerland) · 2024Article
- Transovarial transmission of Yersinia pestis in its flea vector Xenopsylla cheopis.Nature communications · 2024Article
- Review of genotyping methods for Yersinia pestis in Madagascar.PLoS neglected tropical diseases · 2024Review
- Socio-ecological risk factors associated with human flea infestations of rural household in plague-endemic areas of Madagascar.PLoS neglected tropical diseases · 2024Article
- Multiple Introductions of Yersinia pestis during Urban Pneumonic Plague Epidemic, Madagascar, 2017.Emerging infectious diseases · 2024Article
31 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plague, a zoonosis caused by Yersinia pestis, is still found in Africa, Asia, and the Americas. Madagascar reports almost one third of the cases worldwide. Y. pestis can be encountered in three very different types of foci: urban, rural, and sylvatic. Flea vector and wild rodent host population dynamics are tightly correlated with modulation of climatic conditions, an association that could be crucial for both the maintenance of foci and human plague epidemics. The black rat Rattus rattus, the main host of Y. pestis in Madagascar, is found to exhibit high resistance to plague in endemic areas, opposing the concept of high mortality rates among rats exposed to the infection. Also, endemic fleas could play an essential role in maintenance of the foci. This review discusses recent advances in the understanding of the role of these factors as well as human behavior in the persistence of plague in Madagascar.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.