ArticlePloS one2013
Chlorophyll deficiency in the maize elongated mesocotyl2 mutant is caused by a defective heme oxygenase and delaying grana stacking.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed, 58 citations in OpenAlex.
- Natural variation in tetrapyrrole biosynthetic enzymes and their regulation modifies the maize chlorophyll mutant Oy1-N1989.Plant physiology · 2025Article
- ZmDof08, a zinc finger transcription factor, plays critical roles in photosynthesis in maize.Plant cell reports · 2025Article
- Map-based cloning and characterization ofMolecular breeding : new strategies in plant improvement · 2024Article
- Transcriptome Analysis Revealed ZmPTOX1 Is Required for Seedling Development and Stress Tolerance in Maize.Plants (Basel, Switzerland) · 2024Article
- Biochemical and Transcriptome Analysis Reveals Pigment Biosynthesis Influenced Chlorina Leaf Formation in Anoectochilus roxburghii (Wall.) Lindl.Biochemical genetics · 2024Article
- Exogenous Serotonin (5-HT) Promotes Mesocotyl and Coleoptile Elongation in Maize Seedlings under Deep-Seeding Stress through Enhancing Auxin Accumulation and Inhibiting Lignin Formation.International journal of molecular sciences · 2023Article
- White and green striate leaves 1, predicted to encode a 16S rRNA processing protein, plays a critical role in the processing of chloroplast ribosomes in maize (Molecular breeding : new strategies in plant improvement · 2023Article
- A large deletion conferring pale green leaves of maize.BMC plant biology · 2023Article
- Analysis of morphological traits and regulatory mechanism of a semi-dwarf, albino, and blue grain wheat line.Molecular breeding : new strategies in plant improvement · 2023Article
- Article
- Identification and fine mapping of a recessive gene controlling zebra leaf phenotype in maize.Molecular breeding : new strategies in plant improvement · 2021Article
- Using single-plant-omics in the field to link maize genes to functions and phenotypes.Molecular systems biology · 2020Article
- Identification of two recessive etiolation genes (py1, py2) in pakchoi (Brassica rapa L. ssp. chinensis).BMC plant biology · 2020Article
- Review
- Map-Based Cloning and Functional Analysis ofInternational journal of molecular sciences · 2019Article
- Mesophyll-specific phytochromes impact chlorophyll light-harvesting complexes (LHCs) and non-photochemical quenching.Plant signaling & behavior · 2019Article
- Dynamic transcriptome and phytohormone profiling along the time of light exposure in the mesocotyl of rice seedling.Scientific reports · 2017Article
- Heme oxygenase 1 defects lead to reduced chlorophyll in Brassica napus.Plant molecular biology · 2017Article
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Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEtiolated seedlings initiate grana stacking and chlorophyll biosynthesis in parallel with the first exposure to light, during which phytochromes play an important role. Functional phytochromes are biosynthesized separately for two components. One phytochrome is biosynthesized for apoprotein and the other is biosynthesized for the chromophore that includes heme oxygenase (HO). METHODOLOGY/PRINCIPAL FINDING: We isolated a ho1 homolog by map-based cloning of a maize elongated mesocotyl2 (elm2) mutant. cDNA sequencing of the ho1 homolog in elm2 revealed a 31 bp deletion. De-etiolation responses to red and far-red light were disrupted in elm2 seedlings, with a pronounced elongation of the mesocotyl. The endogenous HO activity in the elm2 mutant decreased remarkably. Transgenic complementation further confirmed the dysfunction in the maize ho1 gene. Moreover, non-appressed thylakoids were specifically stacked at the seedling stage in the elm2 mutant.
conclusionThe 31 bp deletion in the ho1 gene resulted in a decrease in endogenous HO activity and disrupted the de-etiolation responses to red and far-red light. The specific stacking of non-appressed thylakoids suggested that the chlorophyll biosynthesis regulated by HO1 is achieved by coordinating the heme level with the regulation of grana stacking.
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