ArticlePloS one2013
Prospective association between dietary fiber intake and breast cancer risk.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 5 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Use of Dietary Fibers in Reducing the Risk of Several Cancer Types: An Umbrella Review.Nutrients · 2023Pooled it
- Association between whole grain intake and breast cancer risk: a systematic review and meta-analysis of observational studies.Nutrition journal · 2018Pooled it
- Dietary fibre intake and risk of breast cancer: A systematic review and meta-analysis of epidemiological studies.Oncotarget · 2016Pooled it
- Dietary Protein Sources and Incidence of Breast Cancer: A Dose-Response Meta-Analysis of Prospective Studies.Nutrients · 2016Pooled it
- Consumption of whole grains and cereal fiber in relation to cancer risk: a systematic review of longitudinal studies.Nutrition reviews · 2016Pooled it
- Dietary soluble, insoluble, and total fiber intake and their dietary sources in association with breast cancer.BMC public health · 2024Article
- Benefits of maternal pectin supplementation in gestation diet on vaginal microbiota of sows and intestinal health of newborn piglets.Frontiers in veterinary science · 2024Article
- Dietary patterns with combined and site-specific cancer incidence in Alberta's Tomorrow Project cohort.European journal of clinical nutrition · 2022Article
- Association of dietaryFrontiers in nutrition · 2022Article
- Long-Term Whole Grain Wheat and Rye Intake Reflected by Adipose Tissue Alkylresorcinols and Breast Cancer: A Case-Cohort Study.Nutrients · 2019Article
- The Benefits of Dietary Fiber Intake on Reducing the Risk of Cancer: An Umbrella Review of Meta-analyses.Journal of chiropractic medicine · 2018Review
- Intake of bean fiber, beans, and grains and reduced risk of hormone receptor-negative breast cancer: the San Francisco Bay Area Breast Cancer Study.Cancer medicine · 2018Article
- Assessing the Racial and Ethnic Disparities in Breast Cancer Mortality in the United States.International journal of environmental research and public health · 2017Review
- Bioavailable insulin-like growth factor-I as mediator of racial disparity in obesity-relevant breast and colorectal cancer risk among postmenopausal women.Menopause (New York, N.Y.) · 2017Observational
- Dietary Fiber Intake in Young Adults and Breast Cancer Risk.Pediatrics · 2016Article
- Dietary patterns and breast cancer: a case-control study in women.European journal of nutrition · 2015Article
- Risk determination and prevention of breast cancer.Breast cancer research : BCR · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMechanistic hypotheses suggest a potential effect of dietary fiber on breast carcinogenesis through the modulation of insulin-like growth factor bioactivity, estrogen metabolism and inflammation. An association between dietary fiber intake and breast cancer risk has been suggested in epidemiological studies but remains inconclusive. In particular, data is lacking regarding the different types of dietary fibers.
objectiveThe objective was to investigate the prospective relationship between dietary fiber intake and breast cancer risk, taking into account different types of dietary fiber (overall, insoluble, soluble and from different food sources: cereals, vegetables, fruits and legumes).
design4684 women from the SU.VI.MAX cohort were included in this analysis as they completed at least three 24h-dietary records within the first two years of follow-up. Among them, 167 incident invasive breast cancers were diagnosed during a median follow-up of 12.6 years (between 1994 and 2007). The associations between quartiles of dietary fiber intake and breast cancer risk were characterized using multivariate Cox proportional hazards models.
resultsTotal fiber intake was not associated with breast cancer risk (HR(Quartile4vs.Quartile1) = 1.29 (95%CI 0.66-2.50), P-trend = 0.5), nor was fiber intake from cereals (P-trend = 0.1), fruits (P-trend = 0.9) and legumes (P-trend = 0.3). In contrast, vegetable fiber intake was related to a decreased risk of breast cancer (HR(Q4vs.Q1) = 0.50 (0.29-0.88), P-trend = 0.03). Overall vegetable intake (in g/day) was not associated with breast cancer risk (P-trend = 0.2).
conclusionThis prospective study suggests that vegetable fiber intake may contribute to reduce breast cancer risk, in line with experimental mechanistic data.
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