ArticlePloS one2013
A new equation to estimate glomerular filtration rate in Chinese elderly population.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparisons of GFR estimation using the CKD Epidemiology Collaboration (CKD-EPI) equation and other creatinine-based equations in Asian population: a systematic review.International urology and nephrology · 2016Pooled it
- Predictors of Health-Related Quality of Life in Patients with Co-Morbid Diabetes and Chronic Kidney Disease.PloS one · 2016Trial
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- Development and validation of a preoperative prediction model for geriatric emergency general surgery.Langenbeck's archives of surgery · 2025Article
- Systemic immune inflammatory index and mortality in chronic kidney disease.Frontiers in endocrinology · 2025Article
- Predictors of quality of life among caregivers of patients with moderate to severe kidney disease: an Australian cross-sectional study.Health and quality of life outcomes · 2024Article
- Clinical surveillance of split renal function inQuantitative imaging in medicine and surgery · 2024Article
- Association between serum uric acid variability and mild eGFR decline in Chinese adults: a retrospective cohort study.BMC nephrology · 2024Article
- Correlation between the increase in serum uric acid and the rapid decline in kidney function in adults with normal kidney function: a retrospective study in Urumqi, China.BMC nephrology · 2023Article
- Cardiovascular Disease Risk Among Cancer Survivors: The Atherosclerosis Risk In Communities (ARIC) Study.Journal of the American College of Cardiology · 2022Article
- Obesity, Galectin-3, and Incident Heart Failure: The ARIC Study.Journal of the American Heart Association · 2022Article
- Glomerular filtration in the aging population.Frontiers in medicine · 2022Review
- Does preoperative serum creatinine affect the early surgical outcomes of acute Stanford type A aortic dissection?Journal of the Chinese Medical Association : JCMA · 2020Article
- Plasma triglyceride levels and central obesity predict the development of kidney injury in Chinese community older adults.Renal failure · 2019Observational
- The Prevalence of Hypertension Accompanied by High Homocysteine and its Risk Factors in a Rural Population: A Cross-Sectional Study from Northeast China.International journal of environmental research and public health · 2017Article
- Observational
- Gender-specific association of decreased estimated glomerular filtration rate and left vertical geometry in the general population from rural Northeast China.BMC cardiovascular disorders · 2017Article
- Visceral Adiposity Index and Lipid Accumulation Product Index: Two Alternate Body Indices to Identify Chronic Kidney Disease among the Rural Population in Northeast China.International journal of environmental research and public health · 2016Article
- Glomerular filtration rate measured by (99m) Tc-DTPA renal dynamic imaging is significantly lower than that estimated by the CKD-EPI equation in horseshoe kidney patients.Nephrology (Carlton, Vic.) · 2016Article
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Authors and funding
10 authors.
Funding
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Abstract
backgroundWe sought to develop a new equation to estimate glomerular filtration rate (GFR) in Chinese elderly population.
methodsA total of 668 Chinese elderly participants, including the development cohort (n = 433), the validation cohort (n = 235) were enrolled. The new equation using the generalized additive model, and age, gender, serum creatinine as predictor variables was developed and the performances was compared with the CKD-EPI equation.
resultsIn the validation data set, both bias and precision were improved with the new equation, as compared with the CKD-EPI equation (median difference, -1.5 ml/min/1.73 m(2) vs. 7.4 ml/min/1.73 m(2) for the new equation and the CKD-EPI equation, [P<0.001]; interquartile range [IQR] for the difference, 16.2 ml/min/1.73 m(2) vs. 19.0 ml/min/1.73 m(2) [P<0.001]), as were accuracies (15% accuracy, 40.4% vs. 30.6% [P = 0.02]; 30% accuracy, 71.1% vs. 47.2%, [P<0.001]; 50% accuracy, 90.2% vs. 75.7%, [P<0.001]), allowing improvement in GFR categorization (GFR category misclassification rate, 37.4% vs. 53.2% [P = <0.001]).
conclusionsA new equation was developed in Chinese elderly population. In the validation data set, the new equation performed better than the original CKD-EPI equation. The new equation needs further external validations. Calibration of the GFR referent standard to a more accurate one should be an useful way to improve the performance of GFR estimating equations.
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