ArticlePloS one2013
Rapid differentiation between livestock-associated and livestock-independent Staphylococcus aureus CC398 clades.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed.
- Brief report: community-associated invasive infection caused by PVL-positive ST1232 (CC398) MRSA in a 15-year-old patient, Poland, 2024.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Prevalence and Characterization ofMicroorganisms · 2025Article
- Time-calibrated phylogenetic and chromosomal mobilome analyses of Staphylococcus aureus CC398 reveal geographical and host-related evolution.Nature communications · 2024Article
- Article
- Antibiotic resistance andHealth science reports · 2023Article
- MRSA in Humans, Pets and Livestock in Portugal: Where We Came from and Where We Are Going.Pathogens (Basel, Switzerland) · 2022Review
- Antimicrobial Resistance and Molecular Epidemiology ofPathogens (Basel, Switzerland) · 2022Article
- A Survey of Chinese Pig Farms and Human Healthcare Isolates Reveals Separate Human and Animal Methicillin-Resistant Staphylococcus aureus Populations.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2022Article
- Genetic characterization of livestock-associated methicillin-resistant Staphylococcus aureus isolated in Greece.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021Article
- Prevalence and Characteristics of Multidrug-Resistant Livestock-Associated Methicillin-ResistantAnimals : an open access journal from MDPI · 2021Article
- Getting ahead of antibiotic-resistant Staphylococcus aureus in U.S. hogs.Environmental research · 2021Article
- Prevalence and characterization ofJAC-antimicrobial resistance · 2021Article
- Detection, molecular characterization, and antibiogram of multi-drug resistant and methicillin-resistantIranian journal of veterinary research · 2021Article
- Arthritis Caused by MRSA CC398 in Patient without Animal Contact, Japan.Emerging infectious diseases · 2020Article
- Characterization of highly virulent community-associated methicillin-resistantEmerging microbes & infections · 2020Article
- Exoproteomic profiling uncovers critical determinants for virulence of livestock-associated and human-originatedVirulence · 2020Article
- Simultaneous Nasal Carriage by Methicillin-Resistant and Methicillin SusceptiblePathogens (Basel, Switzerland) · 2020Article
- International travel as source of a hospital outbreak with an unusual meticillin-resistantEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019Article
- Article
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17 authors.
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Abstract
Staphylococcus aureus clonal complex 398 (CC398) isolates cluster into two distinct phylogenetic clades based on single-nucleotide polymorphisms (SNPs) revealing a basal human clade and a more derived livestock clade. The scn and tet(M) genes are strongly associated with the human and the livestock clade, respectively, due to loss and acquisition of mobile genetic elements. We present canonical single-nucleotide polymorphism (canSNP) assays that differentiate the two major host-associated S. aureus CC398 clades and a duplex PCR assay for detection of scn and tet(M). The canSNP assays correctly placed 88 S. aureus CC398 isolates from a reference collection into the human and livestock clades and the duplex PCR assay correctly identified scn and tet(M). The assays were successfully applied to a geographically diverse collection of 272 human S. aureus CC398 isolates. The simple assays described here generate signals comparable to a whole-genome phylogeny for major clade assignment and are easily integrated into S. aureus CC398 surveillance programs and epidemiological studies.
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