Trial reportPloS one2013
Impaired temporal processing of tactile and proprioceptive stimuli in cerebellar degeneration.
Trial report in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Mind the gap: the temporal discrimination threshold of tactile sensation from implanted peripheral nerve stimulation.Journal of neuroengineering and rehabilitation · 2026Trial
- Exploring somatosensory temporal discrimination deficits in rheumatoid arthritis: associations with disease activity and functionality.Advances in rheumatology (London, England) · 2025Article
- Upper Limb Function but Not Proprioception is Impaired in Essential Tremor: A Between-Groups Study and Causal Mediation Analysis.Tremor and other hyperkinetic movements (New York, N.Y.) · 2023Article
- Neural Correlates of Abnormal Temporal Discrimination in Unaffected Relatives of Cervical Dystonia Patients.Frontiers in integrative neuroscience · 2019Article
- Temporal Discrimination Thresholds and Proprioceptive Performance: Impact of Age and Nerve Conduction.Frontiers in neuroscience · 2019Article
- An approach to monitoring home-cage behavior in mice that facilitates data sharing.Nature protocols · 2018Article
- Temporal Discrimination: Mechanisms and Relevance to Adult-Onset Dystonia.Frontiers in neurology · 2017Review
- When Non-Dominant Is Better than Dominant: Kinesiotape Modulates Asymmetries in Timed Performance during a Synchronization-Continuation Task.Frontiers in integrative neuroscience · 2017Article
- Cerebellar contributions to self-motion perception: evidence from patients with congenital cerebellar agenesis.Journal of neurophysiology · 2016Article
- Consensus paper: the role of the cerebellum in perceptual processes.Cerebellum (London, England) · 2015Review
- Cervical dystonia: a disorder of the midbrain network for covert attentional orienting.Frontiers in neurology · 2014Review
- Tactile and proprioceptive temporal discrimination are impaired in functional tremor.PloS one · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Performance of timed motor sequences relies on the cerebellum and basal ganglia, which integrate proprioceptive information during the motor task and set internal timing mechanisms. Accordingly, these structures are also involved in other temporal processes, such as the discrimination of the different afferent information in the domain of time. In the present study we tested temporal processing of proprioceptive and tactile stimuli in 20 patients with neurodegenerative cerebellar ataxia and 20 age- and sex-matched healthy subjects. Tactile temporal discrimination threshold was defined as the value at which subjects recognized the two stimuli as asynchronous. Temporal discrimination movement threshold of the first dorsal interosseous and flexor carpi radialis was defined as the shortest interval between two paired electrical stimuli in which the subjects blindfolded perceived two separate index finger abductions and wrist flexions. Both tactile and movement temporal discrimination thresholds were higher in patients with cerebellar ataxia. No correlation was found with disease duration and severity. Our study demonstrates that temporal processing of tactile and proprioceptive stimuli is impaired in patients with cerebellar neurodegeneration and highlights the involvement of cerebellum in temporal processing of somatosensory stimuli of different type.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.