ArticleNeoReviews2013
Neonatal Cholestasis.
Article in NeoReviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 55 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Descriptive Study on Patterns of Persistent Neonatal Jaundice on Neonates and Children at Assiut University Children Hospital
Evaluation of the Effectiveness of Stool Color Card in the Early Detection of Biliary Atresia: A Prospective Study.
Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it, 122 citations in OpenAlex.
- Serum predictors of native liver survival post-Kasai: Systematic review and meta-analysis.Journal of pediatric gastroenterology and nutrition · 2026Pooled it
- Case Report: Early recognition of neonatal alpha-1 antitrypsin deficiency: a case of subtle presentation and prompt diagnosis.Frontiers in pediatrics · 2026Article
- The Use of Gadoxetic Acid-Enhanced MRI as a Diagnostic Tool in Cases of Biliary Atresia: A Two-Case Report.Sisli Etfal Hastanesi tip bulteni · 2026Article
- Clinical characteristics and associated factors of cholestasis in infant's ≤3 months with cytomegalovirus infection.Frontiers in microbiology · 2026Article
- Does thyroid function disorder play a vital role in the pathogenesis of neonatal cholestasis?Clinical and experimental hepatology · 2025Article
- Homozygous variants in WDR83OS lead to a neurodevelopmental disorder with hypercholanemia.American journal of human genetics · 2024Article
- Incidence and Risk Factors of Cholestasis in Newborns with Hemolytic Disease-A Case-Control Study.Journal of clinical medicine · 2024Article
- Severe Cholestasis in Neonates with Hemolytic Disease of the Fetus and Newborn-A Case Report.Journal of clinical medicine · 2024Article
- Liver Dysfunction with Severe Cholestasis and Coagulation Disorders in the Course of Hemolytic Disease of the Newborn Requiring Chelation Therapy-A Case Report and Review of the Literature.Journal of clinical medicine · 2023Article
- Bone Status and Early Nutrition in Preterm Newborns with and without Intrauterine Growth Restriction.Nutrients · 2023Article
- Biliary atresia and posterior fossa bleed: Chance or causality. A case report and review of the literature.Clinical case reports · 2023Article
- Towards a model of biliary atresia - Pilot feasibility study in newborn piglets.Biochemistry and biophysics reports · 2023Article
- Article
- Morphological aspects of small-duct cholangiopathies: A minireview.World journal of hepatology · 2023Review
- Cholestasis and congenital neuroblastoma in a preterm neonate: a case report.Case reports in perinatal medicine · 2023Article
- Neonatal Lupus presenting with neonatal hemochromatosis-like liver disease that responded to steroids: a case report.BMC pediatrics · 2022Article
- Pathogenic Novel Heterozygous Variant c.1076c>T p. (Ser359Phe) chr1: 120512166 in NOTCH2 Gene, Type 2 Alagille Syndrome Causing Neonatal Cholestasis: A Case Report.The American journal of case reports · 2022Article
- Cholestasis alters brain lipid and bile acid composition and compromises motor function in neonatal piglets.Physiological reports · 2022Article
- Etiology of neonatal cholestasis after emerging molecular diagnostics.Translational pediatrics · 2022Article
- Ursodeoxycholic Acid and SMOFlipid for Treating Parenteral Nutrition Associated Cholestasis in Infants.Cureus · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Cholestatic jaundice is a common presenting feature of neonatal hepatobiliary and metabolic dysfunction. Any infant who remains jaundiced beyond age 2 to 3 weeks should have the serum bilirubin level fractionated into a conjugated (direct) and unconjugated (indirect) portion. Conjugated hyperbilirubinemia is never physiologic or normal. The differential diagnosis of cholestasis is extensive, and a step-wise approach based on the initial history and physical examination is useful to rapidly identify the underlying etiology. Early recognition of neonatal cholestasis is essential to ensure timely treatment and optimal prognosis. Even when specific treatment is not available, infants who have cholestasis benefit from early medical management and optimization of nutrition. Future studies are necessary to determine the most reliable and cost-effective method of universal screening for neonatal cholestasis.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.