ArticleTopics in spinal cord injury rehabilitation2013
Restoring voluntary grasping function in individuals with incomplete chronic spinal cord injury: pilot study.
Article in Topics in spinal cord injury rehabilitation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 4 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Noninvasive Electromagnetic Neuromodulation of the Central and Peripheral Nervous System for Upper-Limb Motor Strength and Functionality in Individuals with Cervical Spinal Cord Injury: A Systematic Review and Meta-Analysis.Sensors (Basel, Switzerland) · 2024Pooled it
- Pooled it
- Physiotherapy interventions for increasing muscle strength in people with spinal cord injuries: a systematic review.Spinal cord · 2019Pooled it
- The effectiveness of 22 commonly administered physiotherapy interventions for people with spinal cord injury: a systematic review.Spinal cord · 2016Pooled it
- Feasibility of home hand rehabilitation using musicglove after chronic spinal cord injury.Spinal cord series and cases · 2022Trial
- Development of 3D-printed myoelectric hand orthosis for patients with spinal cord injury.Journal of neuroengineering and rehabilitation · 2019Trial
- Trial
- A randomized trial of functional electrical stimulation for walking in incomplete spinal cord injury: Effects on walking competency.The journal of spinal cord medicine · 2014Trial
- The role of surface EMG in predicting responsiveness of muscles to FES therapy after cervical SCI.Journal of neuroengineering and rehabilitation · 2025Article
- Effects of Low Intensity Focused Ultrasound Stimulation Combined With Functional Electrical Stimulation on Corticospinal Excitability and Upper Extremity Fine Motor Function.Brain and behavior · 2025Article
- Boosting brain-computer interfaces with functional electrical stimulation: potential applications in people with locked-in syndrome.Journal of neuroengineering and rehabilitation · 2023Review
- Manipulating facial musculature with functional electrical stimulation as an intervention for major depressive disorder: a focused search of literature for a proposal.Journal of neuroengineering and rehabilitation · 2023Review
- Functional electrical stimulation therapy for upper extremity rehabilitation following spinal cord injury: a pilot study.Spinal cord series and cases · 2023Article
- NeuroSuitUp: System Architecture and Validation of a Motor Rehabilitation Wearable Robotics and Serious Game Platform.Sensors (Basel, Switzerland) · 2023Article
- Compounds co-targeting kinases in axon regulatory pathways promote regeneration and behavioral recovery after spinal cord injury in mice.Experimental neurology · 2022Article
- Epidural electrical stimulation of the cervical dorsal roots restores voluntary upper limb control in paralyzed monkeys.Nature neuroscience · 2022Article
- Soft robotics and functional electrical stimulation advances for restoring hand function in people with SCI: a narrative review, clinical guidelines and future directions.Journal of neuroengineering and rehabilitation · 2022Review
- Multi-center, single-blind randomized controlled trial comparing functional electrical stimulation therapy to conventional therapy in incomplete tetraplegia.Frontiers in rehabilitation sciences · 2022Article
- Current progress of rehabilitative strategies in stem cell therapy for spinal cord injury: a review.NPJ Regenerative medicine · 2021Review
- Brain-computer interface-triggered functional electrical stimulation therapy for rehabilitation of reaching and grasping after spinal cord injury: a feasibility study.Spinal cord series and cases · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFunctional electrical stimulation (FES) therapy has been shown to be one of the most promising approaches for improving voluntary grasping function in individuals with subacute cervical spinal cord injury (SCI).
objectiveTo determine the effectiveness of FES therapy, as compared to conventional occupational therapy (COT), in improving voluntary hand function in individuals with chronic (≥24 months post injury), incomplete (American Spinal Injury Association Impairment Scale [AIS] B-D), C4 to C7 SCI.
methodsEight participants were randomized to the intervention group (FES therapy; n = 5) or the control group (COT; n = 3). Both groups received 39 hours of therapy over 13 to 16 weeks. The primary outcome measure was the Toronto Rehabilitation Institute-Hand Function Test (TRI-HFT), and the secondary outcome measures were Graded Redefined Assessment of Strength Sensibility and Prehension (GRASSP), Functional Independence Measure (FIM) self-care subscore, and Spinal Cord Independence Measure (SCIM) self-care subscore. Outcome assessments were performed at baseline, after 39 sessions of therapy, and at 6 months following the baseline assessment.
resultsAfter 39 sessions of therapy, the intervention group improved by 5.8 points on the TRI-HFT's Object Manipulation Task, whereas the control group changed by only 1.17 points. Similarly, after 39 sessions of therapy, the intervention group improved by 4.6 points on the FIM self-care subscore, whereas the control group did not change at all.
conclusionThe results of the pilot data justify a clinical trial to compare FES therapy and COT alone to improve voluntary hand function in individuals with chronic incomplete tetraplegia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.