Evidence map›Paper›PMID 24242818›Full record

ReviewImmunologic research2013

The evolving art of hematopoietic stem cell transplantation: translational research in post-transplant immune reconstitution and immunosuppression.

Krishna V Komanduri, Eric D Wieder, Cara L Benjamin, Robert B Levy

Abstract readReview
PubMed Publisher
In one paragraph

Review in Immunologic research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Artificial Intelligence Approaches in Hematopoietic Cell Transplantation: A Review of the Current Status and Future DirectionsTurkish journal of haematology : official journal of Turkish Society of Haematology · 2018
    Review
  3. Peritransplantation Red Blood Cell Transfusion Is Associated with Increased Risk of Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2018
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Krishna V KomanduriAdult Stem Cell Transplant Program, Department of Medicine, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL, 33136, USA, kkomanduri@med.miami.edu.
Eric D Wieder
Cara L Benjamin
Robert B Levy

Funding

T Cell Reconstitution After Allogeneic SCTR01CA109326 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KOMANDURI, KRISHNA V. · 2005 to 2009
$1.3M
NCI NIH HHS NCI RO1 CA109326PHS HHS NHLBI RO1 HL091749
6 · The paper itself

Abstract

Allogeneic hematopoietic stem cell transplantation (SCT) offers the best chance for cure and/or long-term survival for a broad range of diseases, including many high-risk hematologic malignancies, bone marrow failure states and subsets of inherited metabolic diseases and hemoglobinopathies. Clinical advances in allogeneic SCT have resulted in dramatically improved clinical outcomes over the past two decades, resulting in a significant expansion of transplant utilization to many recipients who would previously have been excluded from consideration, including elderly recipients and individuals lacking matched sibling or unrelated donors. Despite these advances, significant clinical challenges remain, including delayed immune reconstitution and the frequent occurrence of acute and chronic graft-versus-host disease, especially in the unrelated donor transplant setting. Translational laboratory efforts, facilitated by technical advances in our ability to measure thymopoiesis and functional T cell subsets in humans, have resulted in an improved understanding of immune recovery and have provided novel insights that may lead to more rational and selective immunosuppression.

Indexed as

Transplantation ImmunologyCord Blood Stem Cell TransplantationGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansImmunologic MemoryImmunomodulationImmunophenotypingImmunosuppression TherapyLymphocyte ActivationLymphopoiesisSignal TransductionThymus GlandT-Lymphocyte SubsetsTranslational Research, BiomedicalTransplantation, Homologous

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.