SynthesisAnnals of surgery2014
Strategies for reducing regional variation in the use of surgery: a systematic review.
Synthesis in Annals of surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed.
- Global Perspectives on Radiotherapy Utilization for Pancreatic Ductal Adenocarcinoma.Journal of gastrointestinal cancer · 2026Article
- Development of a core outcome set for the evaluation of shared decision-making interventions in healthcare: a study protocol.BMJ open · 2026Article
- Regional Variation in Wrist Ligament Surgery Incidence: A 25-year Nationwide Register Study.Plastic and reconstructive surgery. Global open · 2026Article
- Examining variations in the prevalence of hazardous opioid prescribing across general practices in England: a cross-sectional study.BMJ quality & safety · 2026Article
- Geography and Opportunity: The Influence of Residency Location on Plastic Surgery Resident Case Volume-A 9-year Review of 1902 Graduates.Plastic and reconstructive surgery. Global open · 2026Article
- Quick Cuts: Surgeon Tendency to Operate in Emergency General Surgery.The Journal of surgical research · 2025Article
- German guidelines for the diagnosis and treatment of squamous-cell carcinoma and adenocarcinoma of the esophagus-version 4.0.ESMO gastrointestinal oncology · 2025Review
- Hospital-level variation in hospitalization costs for spinal fusion in the United States.PloS one · 2024Article
- Regional Implicit Racial Bias and Rates of Breast Reconstruction, Complications, and Cost Among US Patients With Breast Cancer.JAMA network open · 2023Article
- Demonstration of Accuracy and Feasibility of Remotely Delivered Oximetry: A Blinded, Controlled, Real-World Study of Regional/Rural Children with Obstructive Sleep Apnoea.Healthcare (Basel, Switzerland) · 2023Article
- Surgical subspecialization is associated with higher rate of rib fracture stabilization: a retrospective database analysis.Trauma surgery & acute care open · 2023Article
- Factors Associated with the Quality and Transparency of National Guidelines: A Mixed-Methods Study.International journal of environmental research and public health · 2022Article
- What's the SCORE? Current management of symptomatic, clinically occult, radiologically evident inguinal hernias.Annals of the Royal College of Surgeons of England · 2022Article
- Association of Treatment Facility Characteristics With Overall Survival After Mohs Micrographic Surgery for T1a-T2a Invasive Melanoma.JAMA dermatology · 2021Article
- Opioids and Gabapentinoids Utilisation and Their Related-Mortality Trends in the United Kingdom Primary Care Setting, 2010-2019: A Cross-National, Population-Based Comparison Study.Frontiers in pharmacology · 2021Article
- The Impact Of Decision Aids On Adults Considering Hip Or Knee Surgery.Health affairs (Project Hope) · 2020Article
- Buruli ulcer treatment: Rate of surgical intervention differs highly between treatment centers in West Africa.PLoS neglected tropical diseases · 2019Article
- Exploring geographic variation in acute appendectomy in Ireland: results from a national registry study.BMJ open · 2019Article
- Enhancing the study of enhanced recovery after thoracic surgery: methodology and population-based approaches for the future.Journal of thoracic disease · 2019Review
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Abstract
objectiveTo review the literature evaluating the effect of practice guidelines and decision aids on use of surgery and regional variation.
backgroundThe use of surgical procedures varies widely across geographic regions. Although practice guidelines and decision aids have been promoted for reducing variation, their true effectiveness is uncertain.
methodsStudies evaluating the influence of clinical practice guidelines or consensus statements, shared decision making and decision aids, or provider feedback of comparative utilization, on rates of surgical procedures were identified through literature searches of Ovid MEDLINE, EMBASE, and Web of Science.
resultsA total of 1946 studies were identified and 27 were included in the final review. Of the 12 studies evaluating implementation of guidelines, 6 reported a significant effect. Those examining overall population-based rates had mixed effects, but all studies evaluating procedure choice described at least a small increase in use of recommended therapy. Three of 5 studies examining the effect of guidelines on regional variation reported a significant reduction after dissemination. Of the 15 studies examining decision aids, 5 revealed significant effects. Many studies of decision aids reported decreases in population-based procedure rates. Nearly all studies evaluating the impact of decision aids on procedure choice reported increases in rates of less invasive procedures. Only one study of decision aids assessed changes in regional variation and found mixed results.
conclusionsBoth practice guidelines and decision aids have been proven effective in many clinical contexts. Expanding the clinical scope of these tools and eliminating barriers to implementation will be essential to further efforts directed toward reducing regional variation in the use of surgery.
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