Evidence map›Paper›PMID 24240283›Full record

ReviewCurrent opinion in pediatrics2013

Genetic influence on athletic performance.

Lisa M Guth, Stephen M Roth

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current opinion in pediatrics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 7 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 7 syntheses or guidelines pooled it, 160 citations in OpenAlex.

  1. The Role ofGenes · 2026
    Pooled it
  2. Role of theInternational journal of environmental research and public health · 2024
    Pooled it
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  13. Durability as an independent parameter of endurance performance in cycling.BMC sports science, medicine & rehabilitation · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lisa M GuthDepartment of Kinesiology, School of Public Health, University of Maryland, College Park, Maryland, USA.
Stephen M Roth
University of Maryland, College Park · US

Funding

PREDOCTORAL TRAINING IN EXERCISE PHYSIOLOGY AND AGINGT32AG000268 · NIA · UNIV OF MARYLAND, COLLEGE PARK · PI HAGBERG, JAMES M · 1999 to 2014
$2.5M
NIA NIH HHS T32 AG000268
6 · The paper itself

Abstract

purpose of reviewTo summarize the existing literature on the genetics of athletic performance, with particular consideration for the relevance to young athletes. RECENT

findingsTwo gene variants, ACE I/D and ACTN3 R577X, have been consistently associated with endurance (ACE I/I) and power-related (ACTN3 R/R) performance, though neither can be considered predictive. The role of genetic variation in injury risk and outcomes is more sparsely studied, but genetic testing for injury susceptibility could be beneficial in protecting young athletes from serious injury. Little information on the association of genetic variation with athletic performance in young athletes is available; however, genetic testing is becoming more popular as a means of talent identification. Despite this increase in the use of such testing, evidence is lacking for the usefulness of genetic testing over traditional talent selection techniques in predicting athletic ability, and careful consideration should be given to the ethical issues surrounding such testing in children. SUMMARY: A favorable genetic profile, when combined with an optimal training environment, is important for elite athletic performance; however, few genes are consistently associated with elite athletic performance, and none are linked strongly enough to warrant their use in predicting athletic success.

Indexed as

AthletesAthletic PerformancePolymorphism, Single NucleotideActininAdolescentArginineAthletic InjuriesCardiovascular SystemChildFemaleGenotypeHumansMaleMuscle StrengthMutation, MissensePeptidyl-Dipeptidase AACE protein, humanActininACTN3 protein, humanArgininePeptidyl-Dipeptidase A

Identifiers

PMID24240283
PMCPMC3993978
OpenAlexW2024679001

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.