ArticleBiochemical and biophysical research communications2014
Community behavior and amyloid-associated phenotypes among a panel of uropathogenic E. coli.
Article in Biochemical and biophysical research communications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Polysaccharides fromFrontiers in cellular and infection microbiology · 2022Article
- Evaluation of Phosphoethanolamine Cellulose Production among Bacterial Communities Using Congo Red Fluorescence.Journal of bacteriology · 2020Article
- Curli of UropathogenicFrontiers in microbiology · 2019Article
- UnravelingMicrobiology insights · 2019Article
- Phosphoethanolamine cellulose enhances curli-mediated adhesion of uropathogenicProceedings of the National Academy of Sciences of the United States of America · 2018Article
- The Congo red derivative FSB binds to curli amyloid fibers and specifically stains curliated E. coli.PloS one · 2018Article
- Expression of Curli byFrontiers in cellular and infection microbiology · 2016Article
- Dimeric and Trimeric Fusion Proteins Generated with Fimbrial Adhesins of UropathogenicFrontiers in cellular and infection microbiology · 2016Article
- The Biology of the Escherichia coli Extracellular Matrix.Microbiology spectrum · 2015Article
- Bottom-up and top-down solid-state NMR approaches for bacterial biofilm matrix composition.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2015Article
- Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Uropathogenic Escherichia coli (UPEC) are the major causative agents of urinary tract infection and engage in a coordinated genetic and molecular cascade to colonize the urinary tract. Disrupting the assembly and/or function of virulence factors and bacterial biofilms has emerged as an attractive target for the development of new therapeutic strategies to prevent and treat urinary tract infection, particularly in the era of increasing antibiotic resistance among human pathogens. UPEC vary widely in their genetic and molecular phenotypes and more data are needed to understand the features that distinguish isolates as more or less virulent and as more robust biofilm formers or poor biofilm formers. Curli are extracellular functional amyloid fibers produced by E. coli that contribute to pathogenesis and influence the host response during urinary tract infection (UTI). We have examined the production of curli and curli-associated phenotypes including biofilm formation among a specific panel of human clinical UPEC that has been studied extensively in the mouse model of UTI. Motility, curli production, and curli-associated biofilm formation attached to plastic were the most prevalent behaviors, shared by most clinical isolates. We discuss these results in the context on the previously reported behavior and phenotypes of these isolates in the murine cystitis model in vivo.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.