ReviewPharmacology, biochemistry, and behavior2014
Pharmacology of serotonin and female sexual behavior.
Review in Pharmacology, biochemistry, and behavior, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 53 citations in OpenAlex.
- Impact of clomipramine postnatal exposure on sexual behavior and reproductive organs in female rats: role of sexual experience.Behavioral and brain functions : BBF · 2026Article
- Uterotropic response to the antidepressant fluoxetine (Prozac) is dependent on a functional serotonin transporter and circulating serotonin.Scientific reports · 2025Article
- Sexual Functioning and Depressive Symptoms in Levothyroxine-Treated Women with Postpartum Thyroiditis and Different Vitamin D Status.Nutrients · 2025Article
- Sexual Functioning and Depressive Symptoms in Women with Postpartum Thyroiditis.Diagnostics (Basel, Switzerland) · 2025Article
- Article
- Combination of low doses of mirtazapine plus venlafaxine produces antidepressant-like effects in rats, without affecting male or female sexual behavior.Psychopharmacology · 2025Article
- On the basis of sex and sleep: the influence of the estrous cycle and sex on sleep-wake behavior.Frontiers in neuroscience · 2024Review
- Characterization of theAnimal biotechnology · 2023Article
- The antidepressant fluoxetine (Prozac®) modulates estrogen signaling in the uterus and alters estrous cycles in mice.Molecular and cellular endocrinology · 2023Article
- Serotonin Signaling Modulates Sexual Receptivity of Virgin Female Drosophila.Neuroscience bulletin · 2022Article
- Protective Effects of Epigallocatechin Gallate for Male Sexual Dysfunction in Streptozotocin-Induced Diabetic Rats.International journal of molecular sciences · 2022Article
- Breath chemical markers of sexual arousal in humans.Scientific reports · 2022Article
- Expression pattern of olfactory receptor genes in human cumulus cells as an indicator for competent oocyte selection.Turkish journal of biology = Turk biyoloji dergisi · 2020Article
- G Protein-Coupled Receptors (GPCRs)-Mediated Calcium Signaling in Ovarian Cancer: Focus on GPCRs activated by Neurotransmitters and Inflammation-Associated Molecules.International journal of molecular sciences · 2019Review
- Modeling Human Sexual Motivation in Rodents: Some Caveats.Frontiers in behavioral neuroscience · 2019Article
- Inhibitory peptidergic modulation ofeLife · 2017Article
- Article
- Effectiveness of cognitive behavioral therapy and fluoxetine on sexual function of women with obsessive compulsive disorder: A double-blind randomized controlled trial.Electronic physician · 2016Article
- New paradigms in GPCR drug discovery.Biochemical pharmacology · 2015Review
- Flibanserin-Stimulated Partner Grooming Reflects Brain Metabolism Changes in Female Marmosets.The journal of sexual medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
In this review, first a historical perspective of serotonin's (5-HT) involvement in female sexual behavior is presented. Then an overview of studies implicating 5-HT is presented. The effect of drugs that increase or decrease CNS levels of 5-HT is reviewed. Evidence is presented that drugs which increase 5-HT have negative effects on female sexual behavior while a decrease in 5-HT is associated with facilitation of sexual behavior. Studies with compounds that act on 5-HT₁, 5-HT₂ or 5-HT₃ receptors are discussed. Most evidence indicates that 5-HT₁A receptor agonists inhibit sexual behavior while 5-HT₂ or 5-HT₃ receptors may exert a positive influence. There is substantial evidence to support a role for 5-HT in the modulation of female consummatory sexual behavior, but studies on the role of 5-HT in other elements of female sexual behavior (e.g. desire, motivation, sexual appetite) are few. Future studies should be directed at determining if these additional components of female sexual behavior are also modulated by 5-HT.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.