Evidence map›Paper›PMID 24239712›Full record

ArticleBrain, behavior, and immunity2014

Depression, C-reactive protein and length of post-operative hospital stay in coronary artery bypass graft surgery patients.

Lydia Poole, Tara Kidd, Elizabeth Leigh, Amy Ronaldson, Marjan Jahangiri, Andrew Steptoe

Open access · hybridAbstract read
In one paragraph

Article in Brain, behavior, and immunity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Does Mental Distress Predict Cardiac Surgical Outcome?The Thoracic and cardiovascular surgeon · 2025
    Article
  5. Article
  6. Article
  7. Review
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  9. Article
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  15. Article
  16. Pre-Operative Cognitive Functioning and Inflammatory and Neuroendocrine Responses to Cardiac Surgery.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lydia PooleDepartment of Epidemiology and Public Health, University College London, 1-19 TorringtonPlace, London, WC1E 6BT. Electronic address: lydia.poole.09@ucl.ac.uk.
Tara KiddDepartment of Epidemiology and Public Health, University College London, 1-19 TorringtonPlace, London, WC1E 6BT.
Elizabeth LeighDepartment of Epidemiology and Public Health, University College London, 1-19 TorringtonPlace, London, WC1E 6BT; Department of Cardiac Surgery, St. George's Hospital, University of London, Blackshaw Road, London, SW17 0QT.
Amy RonaldsonDepartment of Epidemiology and Public Health, University College London, 1-19 TorringtonPlace, London, WC1E 6BT; Department of Cardiac Surgery, St. George's Hospital, University of London, Blackshaw Road, London, SW17 0QT.
Marjan JahangiriDepartment of Cardiac Surgery, St. George's Hospital, University of London, Blackshaw Road, London, SW17 0QT.
Andrew SteptoeDepartment of Epidemiology and Public Health, University College London, 1-19 TorringtonPlace, London, WC1E 6BT.
University College London · GBSt George's Hospital · GB

Funding

British Heart Foundation FS/09/049/27874British Heart Foundation FS/10/55/28414British Heart Foundation RG/10/005/28296
6 · The paper itself

Abstract

This study aimed to explore the role of C-reactive protein (CRP) in mediating the association between greater pre-operative depression symptoms and longer post-operative length of stay in patients undergoing coronary artery bypass graft (CABG) surgery. We used a sample of 145 elective CABG patients and measured depression symptoms using the Beck Depression Inventory (BDI) prior to surgery and collected baseline measures of CRP. Participants were followed up during their in-hospital stay to measure early (1-3 days post-surgery) and persistent (4-8 days post-surgery) CRP responses to surgery. We found that compared with participants with low depression symptoms, those with elevated depression symptoms (BDI>10) prior to CABG were at increased odds of a hospital stay of greater than one week (OR 3.51, 95% CI 1.415-8.693, p=0.007) and that greater persistent CRP responses mediated this association. Further work is needed to explore the exact physiological pathways through which depression and CRP interact to affect recovery in CABG patients.

Indexed as

Length of StayAgedCoronary Artery BypassC-Reactive ProteinDepressionFemaleHumansMaleMiddle AgedC-Reactive ProteinCoronary artery bypass graftingC-reactive proteinDepressionRecovery

Identifiers

PMID24239712
PMCPMC3969589
OpenAlexW2080551959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.