ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2014
Prevalence of and risk factors for substance use among perinatally human immunodeficiency virus-infected and perinatally exposed but uninfected youth.
Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01418014 (Adolescent Master Protocol), which is not on this map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Adolescent Master Protocol
Who cites it
28 citing papers in PubMed, 37 citations in OpenAlex.
- Projected Life Expectancy for Adolescents With HIV in the US.JAMA health forum · 2024Article
- Relationship between brain structural network integrity and emotional symptoms in youth with perinatally-acquired HIV.Brain, behavior, and immunity · 2024Article
- Prevalence and factors associated with substance use among HIV positive youth attending HIV care and treatment centers in Dodoma, Tanzania.AIDS research and therapy · 2022Article
- Self-Management Frameworks for Youth Living with Human Immunodeficiency Virus.Pediatric clinics of North America · 2022Review
- Alcohol and illicit drug use among young people living with HIV compared to their uninfected peers from the Kenyan coast: prevalence and risk indicators.Substance abuse treatment, prevention, and policy · 2021Article
- The Role of Behavioral and Neurocognitive Functioning in Substance Use Among Youth with Perinatally Acquired HIV Infection and Perinatal HIV Exposure Without Infection.AIDS and behavior · 2021Article
- Drug Use Among Adolescents and Young Adults with Unsuppressed HIV Who Use Alcohol: Identifying Patterns of Comorbid Drug Use and Associations with Mental Health.AIDS and behavior · 2020Article
- Bayesian variable selection for multivariate zero-inflated models: Application to microbiome count data.Biostatistics (Oxford, England) · 2020Article
- Psychiatric trajectories across adolescence in perinatally HIV-exposed youth: the role of HIV infection and associations with viral load.AIDS (London, England) · 2020Article
- Biomarkers of oral inflammation in perinatally HIV-infected and perinatally HIV-exposed, uninfected youth.Journal of clinical periodontology · 2019Article
- A Longitudinal Study of Behavioral Risk, Adherence, and Virologic Control in Adolescents Living With HIV in Asia.Journal of acquired immune deficiency syndromes (1999) · 2019Article
- Agreement and Discrepancy on Emotional and Behavioral Problems Between Caregivers and HIV-Infected Children and Adolescents From Uganda.Frontiers in psychiatry · 2019Article
- Behavioural health risks during early adolescence among perinatally HIV-infected South African adolescents and same-age, HIV-uninfected peers.AIDS care · 2019Article
- The association between oral disease and type of antiretroviral therapy among perinatally HIV-infected youth.AIDS (London, England) · 2018Article
- Prospective memory in youth with perinatally-acquired HIV infection.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2018Article
- Oral microbiota in youth with perinatally acquired HIV infection.Microbiome · 2018Article
- Contributions of Disease Severity, Psychosocial Factors, and Cognition to Behavioral Functioning in US Youth Perinatally Exposed to HIV.AIDS and behavior · 2017Article
- Lower total and regional grey matter brain volumes in youth with perinatally-acquired HIV infection: Associations with HIV disease severity, substance use, and cognition.Brain, behavior, and immunity · 2017Article
- Changes in Substance Use Symptoms Across Adolescence in Youth Perinatally Infected with HIV.AIDS and behavior · 2017Article
- Deformed Subcortical Structures Are Related to Past HIV Disease Severity in Youth With Perinatally Acquired HIV Infection.Journal of the Pediatric Infectious Diseases Society · 2016Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
Abstract
purposeThis study examined risk factors associated with recent substance use (SU) among perinatally human immunodeficiency virus (HIV)-infected (PHIV+) and perinatally exposed, uninfected (PHEU) youth and compared SU lifetime prevalence with the general population of United States (U.S.) adolescents.
methodsWe conducted cross-sectional and longitudinal analyses of 511 PHIV+ and PHEU youth (mean age at study entry, 13.2 years; 51% female; 69% PHIV+; and 72% African-American) enrolled in a U.S. multisite prospective cohort study between 2007 and 2009. Substance use data were collected by audio computer-assisted self-interview. Youth Risk Behavior Surveillance System and Monitoring the Future data were used to compare SU lifetime prevalence with U.S. samples.
resultsPerinatal HIV infection was not a statistically significant risk factor for alcohol or marijuana use. Risk factors for alcohol use among PHIV+ youth included higher severity of emotional and conduct problems and alcohol and marijuana use in the home by the caregiver or others. Risk factors for marijuana use among PHIV+ youth included marijuana use in the home, higher severity of conduct problems, and stressful life events. Similar SU risk factors among PHEU youth included SU in the home and higher severity of conduct and emotional problems. Overall lifetime prevalence of SU by age was similar to that in national surveys.
conclusionsAlthough SU lifetime prevalence and risk factors for PHIV+ and PHEU adolescents were similar to national norms, the negative consequences are potentially greater for PHIV+ youth. Prevention efforts should begin before SU initiation and address the family and social environment and youth mental health status.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.