Evidence map›Paper›PMID 24239030›Full record

Trial reportJournal of substance abuse treatment2014

Interim versus standard methadone treatment: a benefit-cost analysis.

Robert P Schwartz, Pierre K Alexandre, Sharon M Kelly, Kevin E O'Grady, Jan Gryczynski, Jerome H Jaffe

Registry-linked trialAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of substance abuse treatment, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00712036 (Entry Into Comprehensive Methadone Treatment Via Interim Maintenance), which is not on this map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00712036 nacompletednot on this map

Entry Into Comprehensive Methadone Treatment Via Interim Maintenance

TypeinterventionalSponsorFriends Research Institute, Inc.Ran2008 to 2011Enrolled230ConditionsOpiate DependenceArmsInterim, Comprehensive, Restored
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Economic Evaluations of Establishing Opioid Overdose Prevention Centers in 12 North American Cities: A Systematic Review.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research · 2024
    Pooled it
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  4. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Robert P SchwartzFriends Research Institute, Baltimore, MD 21201, USA. Electronic address: rschwartz@friendsresearch.org.
Pierre K AlexandreJohns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Sharon M KellyFriends Research Institute, Baltimore, MD 21201, USA.
Kevin E O'GradyDepartment of Psychology, University of Maryland, College Park, MD 20742, USA.
Jan GryczynskiFriends Research Institute, Baltimore, MD 21201, USA.
Jerome H JaffeFriends Research Institute, Baltimore, MD 21201, USA; Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA; University of Maryland School of Medicine, Department of Psychiatry, Baltimore, MD 21201, USA.
Friends Research Institute · USJohns Hopkins University · USUniversity of Maryland, College Park · US

Funding

Services Research on Interim Opioid MaintenanceR01DA013636 · NIDA · FRIENDS RESEARCH INSTITUTE, INC. · PI SCHWARTZ, ROBERT P · 2001 to 2010
$3.1M
NIDA NIH HHS 2R01 DA 13636NIDA NIH HHS R01 DA013636
6 · The paper itself

Abstract

A benefit-cost analysis was conducted as part of a clinical trial in which newly-admitted methadone patients were randomly assigned to interim methadone (IM; methadone without counseling) for the first 4 months of 12 months of methadone treatment or 12 months of methadone with one of two counseling conditions. Health, residential drug treatment, criminal justice costs, and income data in 2010 dollars were obtained at treatment entry, and 4- and 12-month follow-up from 200 participants and program costs were obtained. The net benefits of treatment were greater for the IM condition but controlling for the baseline variables noted above, the difference between conditions in net monetary benefits was not significant. For the combined sample, there was a pre- to post-treatment net benefit of $1470 (95% CI: -$625; $3584) and a benefit-cost ratio of 1.5 (95% CI: 0.8, 2.3), but using our conservative approach to calculating benefits, these values were not significant.

Indexed as

AdultCost-Benefit AnalysisCounselingFemaleHealth Care CostsHumansMaleMethadoneMiddle AgedOpioid-Related DisordersMethadoneBenefit–costInterim methadoneMethadone treatment

Identifiers

PMID24239030
PMCPMC3947051
OpenAlexW2067572671

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.